細(xì)胞周期是細(xì)胞生命活動的基本過程，細(xì)胞在周期時相的變遷中進(jìn)入增值、分化、衰老和死亡等生理狀態(tài)。細(xì)胞周期分為間期和分裂期：間期又分為三期、即DNA合成前期（G1期）、DNA合成期（S期）與DNA合成后期（G2期）；分裂期（M期）又分為前期，中期，后期和末期。
研究發(fā)現(xiàn)在細(xì)胞周期中起非常重要的幾類調(diào)控因子：一類是細(xì)胞生長因子對細(xì)胞分裂增殖有調(diào)控作用，如血小板衍生生長因子PDGF、轉(zhuǎn)化生長因子TGF等；另一類是細(xì)胞周期調(diào)控因子，包括細(xì)胞周期蛋白cyclin、細(xì)胞周期蛋白依賴激酶CDK、CDK抑制因子CKI和促進(jìn)CDK調(diào)節(jié)因子降解的酶復(fù)合物（如SCF和APC酶復(fù)合物）。
由于細(xì)胞周期的失調(diào)與腫瘤的發(fā)生密切相關(guān)，同時細(xì)胞周期調(diào)控因子也參與體內(nèi)多種細(xì)胞分化，因此目前對細(xì)胞周期調(diào)控的研究也是生物學(xué)研究的熱點課題，更深更廣地探討分子間相互作用和基因表達(dá)調(diào)控的機制，為以后腫瘤的治療提供新的思路。
Bioss自2001年成立以來一直致力于科研抗體的研發(fā)、生產(chǎn)、銷售，已研發(fā)出大量有關(guān)細(xì)胞周期研究領(lǐng)域的優(yōu)質(zhì)抗體，其中有轉(zhuǎn)化生長因子（TGF-β）、周期素（Cyclin）和腫瘤抑制基因（p53）等靶標(biāo)抗體，為廣大科研工作者提供優(yōu)質(zhì)的產(chǎn)品和無憂的售后，為生命科學(xué)助力！
Bioss抗體推薦
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細(xì)胞周期檢查點靶標(biāo) |
抗體編號 |
應(yīng)用 |
交叉反應(yīng) |
| ATM | bs-1370R | IHC FCM | Human |
| phospho-ATM (Ser794) | bs-12545R | IHC | Human |
| cdc2 (POH1) | bs-19469R | WB | Human、Rat、Mouse |
| Phospho-cdc25A (Ser76) | bs-3094R | WB | Human、Mouse |
| Phospho-cdc25A (Ser178) | bs-3095R | IHC | Human |
| Phospho-cdc25C (Ser216) | bs-3096R | WB | Mouse |
| Phospho-cdc25C (Thr48) | bs-3482R | IHC | Rat、Mouse |
| cdc25C | bs-9597R | IHC | Human、Rat、Mouse |
| cdc25C | bs-10579R | IHC | Human、Rat、Mouse |
| Phospho-CDK2 (Thr160) | bs-3483R | WB IHC | Human、Mouse |
| CDK2 | bs-10726R | WB FCM | Human、Mouse |
| Chk1 | bs-1681R | WB IHC FCM | Human、Mouse |
| Phospho-CHEK1 (Ser296) | bs-11226R | IHC | Human |
| phospho-CHK1 (Ser286) | bs-13906R | WB | Mouse |
| Chk2 | bs-1391R | WB IHC FCM | Human |
| Phospho-CHK2 (Thr68) | bs-3721R | IHC | Rat |
| Phospho-CHK2 (Ser516) | bs-5257R | WB | Human |
| Phospho-CHK2 (Ser28) | bs-13907R | WB IHC | Human |
| Phospho-CHK2 (Ser33 + Ser35) | bs-13908R | WB | Human |
| Phospho-Cyclin B1 (Ser126) | bs-3733R | IHC | Human |
| Phospho-Cyclin B1 (Ser147) | bs-3122R | FCM | Human |
| Phospho-Cyclin B1 (Ser133) | bs-3123R | FCM | Human |
| Cyclin E1 | bsm-52048R | IHC | Human、Mouse |
| Cyclin E1 | bs-8929R | FCM | Human |
| phospho-Cyclin E1 (Thr77) | bs-3125R | FCM | Human |
| Cyclin E1 | bs-0573R | WB | Human、Mouse |
| Cyclin E2 | bs-23753R | IHC | Mouse |
| Cyclin E2 | bsm-52049R | FCM | Human |
| MDM2 | bs-23748R | WB IHC | Human、Mouse |
| CDKN1A/p21 | bs-0741R | IHC ICC FCM | Human、Rat |
| phospho-CDKN1A/p21 (Thr145) | bs-5237R | IHC | Human、Rat、Mouse |
| phospho-CDKN1A/p21 (Ser146) | bs-5238R | IHC | Human |
| phospho-CDKN1A/p21 (Ser130) | bs-5274R | IHC FCM | Human、Rat、Mouse |
| CDKN1A/p21 | bs-22795R | IHC | Human、Mouse |
| phospho-CDKN1B (Thr157) | bs-5228R | WB IHC FCM | Human、Rat、Mouse |
| phospho-CDKN1B (Ser178) | bs-5236R | WB IHC | Rat、Mouse |
| phospho-CDKN1B (Thr198) | bs-5279R | IHC FCM | Human、Rat、Mouse |
| phospho-CDKN1B (Ser10) | bs-20074R | IHC FCM | Human、Rat、Mouse |
| phospho-P53 (Ser33) | bs-3705R | WB IHC FCM | Human、Mouse |
| P53(Mono Methyl Lys370) | bsm-33209M | WB IHC | Human、Mouse |
| phospho-P53 (Ser37) | bs-3706R | WB | Human |
| phospho-P53 (Thr18) | bs-3710R | WB | Human、Rat、Mouse |
| Wee1 | bs-23526R | IHC | Human |
| Phospho-Wee1 (Ser53) | bs-5589R | IHC | Human、Rat、Mouse |
| Phospho-cdc25A (Ser178) | bs-3095R | IHC | Human |
| Phospho-cdc25A (Ser76) | bs-3094R | WB | Human、Mouse |
