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Rabbit Anti-ANGPTL2  antibody (bs-0537R)  
~~~促銷代碼KT202411~~~
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產(chǎn)品編號 bs-0537R
英文名稱 Rabbit Anti-ANGPTL2  antibody
中文名稱 血管生成素樣蛋白2抗體
別    名 ANGPTL2; Angiopoietin like 2; Angiopoietin related protein 2; Angiopoietin-like protein 2; Angiopoietin-related protein 2; ANGL2_HUMAN; Angptl2; ANGL2; Arp2; HARP; MGC8889.  
研究領(lǐng)域 腫瘤  心血管  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human,Mouse (predicted: Rat,Rabbit,Pig,Cow,Chicken,Dog,Horse)
產(chǎn)品應(yīng)用 WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 55kDa
細(xì)胞定位 分泌型蛋白 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human ANGPTL2: 401-493/493 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 ANGPTL2/ANG-2 (Angiopoietin-like Protein 2) Induces sprouting in endothelial cells through an autocrine and paracrine action. [Subcellular location] Secreted. [Tissue specificity] Widely expressed in heart, small intestine, spleen and stomach. Also found in lower levels in colon, ovary, adrenal gland, skeletal muscle and in prostate. [PTM] N-glycosylated. [Similarity] Contains 1 fibrinogen C-terminal domain. ANGPTL2/ANG-2 (Angiopoietin-like Protein 2).


Function:
Induces sprouting in endothelial cells through an autocrine and paracrine action.

Subcellular Location:
Secreted.

Tissue Specificity:
Widely expressed in heart, small intestine, spleen and stomach. Also found in lower levels in colon, ovary, adrenal gland, skeletal muscle and in prostate.

Similarity:
Contains 1 fibrinogen C-terminal domain.

SWISS:
Q9UKU9

Gene ID:
23452

Database links:

Entrez Gene: 23452 Human

Entrez Gene: 26360 Mouse

Entrez Gene: 171100 Rat

Omim: 605001 Human

SwissProt: Q9UKU9 Human

SwissProt: Q9R045 Mouse

Unigene: 653262 Human

Unigene: 208919 Mouse

Unigene: 162660 Rat



Ang1/2與血管生成關(guān)系最為密切,目前有關(guān)該家族成員在腫瘤血管生成中的研究正日益增多。近年來也用于糖尿病導(dǎo)致的血管損傷研究也是熱門課題.
產(chǎn)品圖片
Sample: Heart (Mouse) Lysate at 40 ug Primary: Anti-ANGPTL2 (bs-0537R) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 55 kD Observed band size: 55 kD
Paraformaldehyde-fixed, paraffin embedded (Human uterine muscle); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (Angptl2) Polyclonal Antibody, Unconjugated (bs-0537R) at 1:200 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
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