產(chǎn)品編號(hào) | bs-0856R |
英文名稱 | Rabbit Anti-SLC34A2 antibody |
中文名稱 | 磷酸鈉協(xié)同轉(zhuǎn)運(yùn)蛋白抗體 |
別 名 | NaPi-2b; Sodium-dependent phosphate transport protein 2B; Sodium/phosphatecotransporter 2B; Na(+)/Pi cotransporter 2B; Sodium-phosphatetransport protein 2B; Na(+)-dependent phosphate cotransporter 2B; Solute carrier family 34 member 2; NPT2B_HUMAN; NaPi3b; SLC34A2; Sodium-dependent phosphate transport protein 2B. |
研究領(lǐng)域 | 細(xì)胞生物 通道蛋白 |
抗體來(lái)源 | Rabbit |
克隆類(lèi)型 | Polyclonal |
交叉反應(yīng) | Rat (predicted: Mouse) |
產(chǎn)品應(yīng)用 | WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理論分子量 | 77kDa |
細(xì)胞定位 | 細(xì)胞膜 |
性 狀 | Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from mouse SLC34A2: 1-50/697 <Cytoplasmic> |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
產(chǎn)品介紹 |
Na+/Pi-cotransporterThis is a family of mainly mammalian type II renal Na+/Pi-cotransporters with other related sequences from lower eukaryotes and bacteria some of which are also Na+/Pi-cotransporters. In the kidney the type II renal Na+/Pi-cotransporters protein allows reabsorption of filtered Pi in the proximal tubule. Function: May be involved in actively transporting phosphate into cells via Na(+) cotransport. It may be the main phosphate transport protein in the intestinal brush border membrane. May have a role in the synthesis of surfactant in lungs' alveoli. Subcellular Location: Membrane; Multi-pass membrane protein. Tissue Specificity: Highly abundant in the ileum of small intestine, whereas it is almost absent in the duodenum and in the jejunum. Similarity: Belongs to the SLC34A transporter family. SWISS: Q9DBP0 Gene ID: 20531 Database links: Entrez Gene: 10568 Human Entrez Gene: 20531 Mouse Omim: 604217 Human SwissProt: O95436 Human Unigene: 479372 Human SLC34A2/NaPi-2b是磷酸鈉協(xié)同轉(zhuǎn)運(yùn)蛋白的基因,表達(dá)在動(dòng)物多種組織中,以肺組織表達(dá)最高。該基因主要參與無(wú)機(jī)磷代謝,與肺泡微石癥、睪丸微石癥等多種代謝性疾病發(fā)病相關(guān)。 |