吃奶呻吟打开双腿做受动态图 -亚洲色偷偷色噜噜狠狠99网-日韩精品极品视频在线观看免费-来一水AV@lysav

掃碼關(guān)注公眾號           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  人才招聘  關(guān)于我們  聯(lián)系我們
国产精品美女WWW爽爽爽视频,成人性爱视频在线观看,永久免费精品精品永久-夜色
首頁 > 產(chǎn)品中心 > 一抗 > 產(chǎn)品信息
Rabbit Anti-Ubiquitin  antibody (bs-1549R)  
訂購熱線:400-901-9800
訂購郵箱:sales@xucheq.com
訂購QQ:  400-901-9800
技術(shù)支持:techsupport@xucheq.com
說明書: 50ul  100ul  200ul
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包裝/詢價

產(chǎn)品編號 bs-1549R
英文名稱 Rabbit Anti-Ubiquitin  antibody
中文名稱 泛素蛋白抗體
別    名 FLJ25987; MGC8385; RPS27A; RPS 27A; UBA52; UBA 52; UBA80; UBA 80; UBB; UBC; UB; UBCEP1; UBCEP2; UBCEP 1; UBCEP 2; UBCEP-1; UBCEP-2; Ubiquitin; ubiquitin B; UBC_HUMAN; UBB_HUMAN; RS27A_HUMAN; HMG20; Ubiquitin carboxyl extension protein 80; Ubiquitin; Polyubiquitin-C; Polyubiquitin-B.  
Specific References  (3)     |     bs-1549R has been referenced in 3 publications.
[IF=6.208] Qiong Zong. et al. Comparative Ubiquitome Analysis Reveals Deubiquitinating Effects Induced by Wolbachia Infection in Drosophila melanogaster. INT J MOL SCI. 2022 Jan;23(16):9459  IP ;  Fly.  
[IF=6.15] Ling Yang. et al. Bergenin, a PPARγ agonist, inhibits Th17 differentiation and subsequent neutrophilic asthma by preventing GLS1-dependent glutaminolysis. Acta Pharmacol Sin. 2021 Jul;:1-14  WB ;  Mouse.  
[IF=3.37] Cheng, Shuang, et al. "The ubiquitin-proteasome system is required for the early stages of porcine circovirus type 2 replication." Virology 456 (2014): 198-204.  WB ;  Pig.  
研究領(lǐng)域 腫瘤  細(xì)胞生物  免疫學(xué)  神經(jīng)生物學(xué)  細(xì)胞凋亡  泛素  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human,Mouse,Rat (predicted: Pig)
產(chǎn)品應(yīng)用 WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,Flow-Cyt=1ug/Test,ICC/IF=1:100,IF=1:100-500
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 8.5kDa
細(xì)胞定位 細(xì)胞核 細(xì)胞漿 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Ubiquitin: 1-76/685 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 This gene encodes ubiquitin, one of the most conserved proteins known. Ubiquitin has a major role in targeting cellular proteins for degradation by the 26S proteosome. It is also involved in the maintenance of chromatin structure, the regulation of gene expression, and the stress response. Ubiquitin is synthesized as a precursor protein consisting of either polyubiquitin chains or a single ubiquitin moiety fused to an unrelated protein. This gene consists of three direct repeats of the ubiquitin coding sequence with no spacer sequence. Consequently, the protein is expressed as a polyubiquitin precursor with a final amino acid after the last repeat. An aberrant form of this protein has been detected in patients with Alzheimer's disease and Down syndrome. Pseudogenes of this gene are located on chromosomes 1, 2, 13, and 17. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]

Function:
Ubiquitin exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repair; Lys-11-linked is involved in ERAD (endoplasmic reticulum-associated degradation) and in cell-cycle regulation; Lys-29-linked is involved in lysosomal degradation; Lys-33-linked is involved in kinase modification; Lys-48-linked is involved in protein degradation via the proteasome; Lys-63-linked is involved in endocytosis, DNA-damage responses as well as in signaling processes leading to activation of the transcription factor NF-kappa-B. Linear polymer chains formed via attachment by the initiator Met lead to cell signaling. Ubiquitin is usually conjugated to Lys residues of target proteins, however, in rare cases, conjugation to Cys or Ser residues has been observed. When polyubiquitin is free (unanchored-polyubiquitin), it also has distinct roles, such as in activation of protein kinases, and in signaling.

Subcellular Location:
Cytoplasm. Nucleus.

Similarity:
Belongs to the ubiquitin family.
Contains 9 ubiquitin-like domains.

SWISS:
P0CG48

Gene ID:
7314

Database links:

Entrez Gene: 281370 Cow

Entrez Gene: 100049794 Horse

Entrez Gene: 7314 Human

Entrez Gene: 22187 Mouse

Entrez Gene: 192255 Rat

Omim: 191339 Human

SwissProt: P0CG53 Cow

SwissProt: Q8MKD1 Horse

SwissProt: P0CG47 Human

SwissProt: P0CG48 Human

SwissProt: P62988 Human

SwissProt: P0CG49 Mouse

SwissProt: P62991 Mouse

SwissProt: P0CG51 Rat

SwissProt: P62989 Rat

Unigene: 356190 Human

Unigene: 520348 Human

Unigene: 282093 Mouse

Unigene: 371592 Mouse

Unigene: 110618 Rat

Unigene: 1253 Rat

Unigene: 3761 Rat



泛素及類泛素蛋白(Ubls) 存在在多種細(xì)胞中,有多種細(xì)胞調(diào)控的功能,如細(xì)胞增殖、凋亡、細(xì)胞周期及DNA修復(fù)等。但泛素途徑的異常會導(dǎo)致人類疾病的產(chǎn)生,包括多種形式的腫瘤的發(fā)生,神經(jīng)退變等都與泛素有關(guān)。

相關(guān)產(chǎn)品:
Ubiquitin 1-76 peptides (bs-10803P);
產(chǎn)品圖片
Sample: Ubiquitin protein at 100ng; Primary: Anti-Ubiquitin (bs-1549R) at 1:300 dilution; Secondary: HRP conjugated Goat-Anti-rabbit IgG(bs-0295G-HRP) at 1: 5000 dilution; Predicted band size: 8.5 kD Observed band size: 8.5 kD
Paraformaldehyde-fixed, paraffin embedded (Mouse pancreas); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (Ubiquitin) Polyclonal Antibody, Unconjugated (bs-1549R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
Paraformaldehyde-fixed, paraffin embedded (Human skin carcinoma); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (Ubiquitin) Polyclonal Antibody, Unconjugated (bs-1549R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
Paraformaldehyde-fixed, paraffin embedded (rat colon tissue); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (Ubiquitin) Polyclonal Antibody, Unconjugated (bs-1549R) at 1:400 overnight at 4°C, followed by a conjugated secondary (sp-0023) for 20 minutes and DAB staining.
HepG2 cell; 4% Paraformaldehyde-fixed; Triton X-100 at room temperature for 20 min; Blocking buffer (normal goat serum, C-0005) at 37°C for 20 min; Antibody incubation with (Ubiquitin) polyclonal Antibody, Unconjugated (bs-1549R) 1:100, 90 minutes at 37°C; followed by a conjugated Goat Anti-Rabbit IgG antibody at 37°C for 90 minutes, DAPI (blue, C02-04002) was used to stain the cell nuclei.
Blank control (Black line): Molt4 (Black). Primary Antibody (green line):Rabbit Anti-Ubiquitin antibody (bs-1549R) Dilution:1μg /10^6 cells; Isotype Control Antibody (orange line): Rabbit IgG . Secondary Antibody (white blue line): Goat anti-rabbit IgG-AF647 Dilution: 1μg /test. Protocol The cells were fixed with 4% PFA (10min at room temperature)and then permeabilized with 90% ice-cold methanol for 20 min at room temperature. The cells were then incubated in 5%BSA to block non-specific protein-protein interactions for 30 min at room temperature .Cells stained with Primary Antibody for 30 min at room temperature. The secondary antibody used for 40 min at room temperature. Acquisition of 20,000 events was performed.
Blank control(black line):HepG2. Primary Antibody (green line): Rabbit Anti-Ubiquitin antibody (bs-1549R) Dilution:1ug/Test; Secondary Antibody : Goat anti-rabbit IgG-AF488 Dilution: 0.5ug/Test. Negative control(white blue line): PBS Isotype control(orange line): Normal Rabbit IgG Protocol The cells were fixed with 4% PFA (10min at room temperature)and then permeabilized with 90% ice-cold methanol for 20 min at -20℃.The cells were then incubated in 5%BSA to block non-specific protein-protein interactions for 30 min at room temperature .Cells stained with Primary Antibody for 30 min at room temperature. The secondary antibody used for 40 min at room temperature. Acquisition of 20,000 events was performed.
版權(quán)所有 2004-2026 www.xucheq.com 北京博奧森生物技術(shù)有限公司
通過國際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網(wǎng)安備110107000727號
嫩草伊人久久精品少妇AV| 免费AV在线| 国产AV天堂无码一区二区三区| 医院人妻闷声隔着帘子被中出| 日本少妇春药特殊按摩3| 国产69精品久久久久777| 国产成人无码AA精品一区 | 无码人妻AV一二区二区三区| 亚洲AV日韩AV无码AV| 亚洲AV无码乱码在线观看| 人妻少妇偷人精品无码| 国产A√精品区二区三区四区| 国产精品无码无卡无需播放器| 国产又黄又爽又猛免费视频播放| 色综合久久精品亚洲国产| 挺进邻居丰满少妇的身体| 麻豆乱码国产一区二区三区| 女人扒开屁股桶爽30分钟| 国产亚洲精品精品精品| 又大又紧又粗C欧美成人在线视频| 成人AV无码一区二区三区| 免费观看a级毛片| 又白又嫩毛又多15P| 国产一区二区三区成人欧美日韩在线观看 | 少妇荡乳情欲办公室456视频| 男男车车的车车网站W98免费| 欧美乱大交XXXXX潮喷| 国产精品色欲AV亚洲三区小说| 日韩欧美亚洲国产精品字幕久久久| 搡BBBB搡BBB搡| 国产在线精品一区二区| 七旬老人为满足需求| 久久久国产打桩机| 免费做爰试看120秒| 18禁裸乳无遮挡啪啪无码免费| 欧美熟妇XXXXX欧美老妇不卡| 蜜桃成人无码区免费视频网站| 亚洲精品乱码久久久久久| 国产精品无码不卡一区二区三区| 双性精跪趴灌满H室友| 国产初高中精品无码专区|