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Rabbit Anti-GPR14  antibody (bs-1806R)  
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50ul/1180.00元
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產(chǎn)品編號 bs-1806R
英文名稱 Rabbit Anti-GPR14  antibody
中文名稱 G蛋白偶聯(lián)受體14抗體
別    名 G protein coupled receptor 14; Urotensin II receptor (UR II R); UTR; UTR2; UTS2R; G Protein Coupled Receptor 14; GPCR GPR14; Urotensin II receptor; UR-II-R; UR-2-R; G-protein coupled receptor 14; G-protein coupled sensory epithelial neuropeptide-like receptor; SENR; GPR14; UR2R_HUMAN; GPCR GPR14.  
Specific References  (1)     |     bs-1806R has been referenced in 1 publications.
[IF=16.806] Bo Gao. et al. Discovery and Application of Postnatal Nucleus Pulposus Progenitors Essential for Intervertebral Disc Homeostasis and Degeneration. 2022 Feb 23  IF ;  Human.  
研究領(lǐng)域 細(xì)胞生物  細(xì)胞膜受體  G蛋白偶聯(lián)受體  G蛋白信號  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human (predicted: Mouse,Rat)
產(chǎn)品應(yīng)用 WB=1:500-2000,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 42kDa
細(xì)胞定位 細(xì)胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human UTS2R: 101-200/389 <Cytoplasmic>
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 GPCR GPR14 has been reported to be expressed at high levels in the heart and pancreas and also in artery and smooth muscle. Low transcript levels have been identified in brain, particularly in thalamus, superior occipital gyrus, and substantia nigra.
GPR14 is a high affinity receptor for urotensin-2 and urotensin-2B. The activity of this receptor is mediated by a G-protein that activates a phosphatidylinositol-calcium second messenger system. Referenced from Swiss-Prot Q9UKP6.

Function:
High affinity receptor for urotensin-2 and urotensin-2B. The activity of this receptor is mediated by a G-protein that activate a phosphatidylinositol-calcium second messenger system.

Subcellular Location:
Cell membrane; Multi-pass membrane protein.

Tissue Specificity:
Most abundant expression in the heart and pancreas.

Similarity:
Belongs to the G-protein coupled receptor 1 family.

SWISS:
Q9UKP6

Gene ID:
2837

Database links:

Entrez Gene: 2837 Human

Entrez Gene: 217369 Mouse

Entrez Gene: 57305 Rat

Omim: 600896 Human

SwissProt: Q9UKP6 Human

SwissProt: Q8VIH9 Mouse

SwissProt: P49684 Rat

Unigene: 192720 Human

Unigene: 20122 Mouse

Unigene: 44230 Rat



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