| 產(chǎn)品編號 | bs-2619R |
| 英文名稱 | Rabbit Anti-IL-20R alpha antibody |
| 中文名稱 | 白介素20受體α鏈抗體 |
| 別 名 | IL-20Rα; Interleukin-20 receptor alpha chain precursor;IL-20RA; IL20 RA; IL-20 RA; E230031K19; FLJ40993; IL-20R1; IL20RA; ZCYTOR7;Interleukin-20 receptor subunit alpha; IL-20 receptor subunit alpha; IL-20R-alpha; IL-20RA; Cytokine receptor family 2 member 8; CRF2-8; Cytokine receptor class-II member 8; I20RA_HUMAN. |
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Specific References (2) | bs-2619R has been referenced in 2 publications.
[IF=6.183] Madouri F et al. Production of Interleukin-20 cytokines limits bacterial clearance and lung inflammation during infection by Streptococcus pneumoniae.(2018) EBioMedicine. Oct 22. IHC ; Mouse.
[IF=5.076] Liu Shengpeng. et al. IL-20R Activation via rIL-19 Enhances Hematoma Resolution through the IL-20R1/ERK/Nrf2 Pathway in an Experimental GMH Rat Pup Model. Oxid Med Cell Longev. 2021;2021:5913424 WB,IF ; Rat.
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| 研究領(lǐng)域 | 細(xì)胞生物 免疫學(xué) 細(xì)胞膜受體 細(xì)胞表面分子 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | Mouse (predicted: Human,Rat,Rabbit,Cow,Dog,Horse) |
| 產(chǎn)品應(yīng)用 | WB=1:500-2000,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 59kDa |
| 細(xì)胞定位 | 細(xì)胞膜 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human IL-20RA: 121-220/553 <Extracellular> |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
The protein encoded by this gene is a receptor for interleukin 20 (IL20), a cytokine that may be involved in epidermal function. The receptor of IL20 is a heterodimeric receptor complex consisting of this protein and interleukin 20 receptor beta (IL20B). This gene and IL20B are highly expressed in skin. The expression of both genes is found to be upregulated in Psoriasis. [provided by RefSeq] Function: The IL20RA/IL20RB dimer is a receptor for IL19, IL20 and IL24. The IL20RA/IL10RB dimer is a receptor for IL26. Subunit: Heterodimer with IL20RB and heterodimer with IL10RB. Subcellular Location: Membrane; Single-pass type I membrane protein. Tissue Specificity: Widely expressed with highest levels in skin and testis and high levels in brain. Highly expressed in psoriatic skin. Similarity: Belongs to the type II cytokine receptor family. Contains 2 fibronectin type-III domains. SWISS: Q9UHF4 Gene ID: 53832 Database links: Entrez Gene: 53832 Human Entrez Gene: 237313 Mouse Omim: 605620 Human SwissProt: Q9UHF4 Human SwissProt: Q6PHB0 Mouse Unigene: 445868 Human Unigene: 234667 Mouse |
| 產(chǎn)品圖片 |
Sample:
Lane 1: Mouse Skin tissue lysates
Lane 2: Mouse Kidney tissue lysates
Lane 3: Mouse Testis tissue lysates
Primary: Anti-IL-20R alpha (bs-2619R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 59 kDa
Observed band size: 59 kDa
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