產(chǎn)品編號(hào) | bs-2159R |
英文名稱 | Rabbit Anti-Glypican 4 antibody |
中文名稱 | 磷脂酰基醇蛋白聚糖-4抗體 |
別 名 | dJ900E8.1 glypican 4; Glypican proteoglycan 4; Gpc4; K Glypican; Kglypican; OTTHUMP00000024052; Secreted glypican 4; GPC4_HUMAN. |
研究領(lǐng)域 | 腫瘤 細(xì)胞生物 免疫學(xué) 神經(jīng)生物學(xué) 信號(hào)轉(zhuǎn)導(dǎo) 干細(xì)胞 細(xì)胞凋亡 細(xì)胞表面分子 |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | Human,Rat (predicted: Mouse,Rabbit,Pig,Cow,Dog,GuineaPig,Horse) |
產(chǎn)品應(yīng)用 | Flow-Cyt=1μg/Test
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
細(xì)胞定位 | 細(xì)胞膜 細(xì)胞外基質(zhì) 分泌型蛋白 |
性 狀 | Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human Glypican 4: 351-450/556 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
產(chǎn)品介紹 |
Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation. The GPC4 gene is adjacent to the 3' end of GPC3 and may also play a role in Simpson-Golabi-Behmel syndrome. [provided by RefSeq, Jul 2008] Function: Cell surface proteoglycan that bears heparan sulfate. May be involved in the development of kidney tubules and of the central nervous system (By similarity). Subcellular Location: Cell membrane; Lipid-anchor, GPI-anchor; Extracellular side (By similarity). Secreted glypican-4: Secreted, extracellular space (By similarity). Similarity: Belongs to the glypican family. SWISS: O75487 Gene ID: 2239 Database links: Entrez Gene: 2239 Human Entrez Gene: 14735 Mouse Omim: 300168 Human SwissProt: O75487 Human SwissProt: P51655 Mouse Unigene: 58367 Human Unigene: 1528 Mouse Unigene: 478164 Mouse |
產(chǎn)品圖片 |
Blank control(blue): U-87MG (fixed with 2% paraformaldehyde (10 min). Primary Antibody:Rabbit Anti-Glypican 4 antibody(bs-2159R), Dilution: 1μg in 100 μL 1X PBS containing 0.5% BSA;
Isotype Control Antibody: Rabbit IgG(orange) ,used under the same conditions ); Secondary Antibody: Goat anti-rabbit IgG-PE(white blue), Dilution: 1:200 in 1 X PBS containing 0.5% BSA.
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