| 產(chǎn)品編號(hào) | bs-2655R |
| 英文名稱 | Rabbit Anti-LTB4-R2 antibody |
| 中文名稱 | 白三烯B4受體2抗體 |
| 別 名 | BLT2R; JULF2; Leukotriene B4 receptor 2; Leukotriene B4 receptor BLT2; LT4R2_HUMAN; LTB4 receptor JULF2; LTB4-R 2; LTB4-R2; LTB4R2; Seven transmembrane receptor BLTR2. |
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Specific References (2) | bs-2655R has been referenced in 2 publications.
[IF=4.57] Zinn, Sebastian, et al. "The leukotriene B4 receptors BLT1 and BLT2 form an antagonistic sensitizing system in peripheral sensory neurons." Journal of Biological Chemistry (2017): jbc-M116. IHC-F ; Mouse.
[IF=0] Wculek, S. Pre-metastatic neutrophils directly support highly tumourigenic breast cancer cells during lung metastasis via a leukotriene-ERK1/2 axis. Diss. UCL (University College London), 2016. FCM ; Mouse.
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| 研究領(lǐng)域 | 腫瘤 心血管 免疫學(xué) 信號(hào)轉(zhuǎn)導(dǎo) 脂蛋白 新陳代謝 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | Human (predicted: Mouse,Rat,Pig,Cow,Dog,GuineaPig) |
| 產(chǎn)品應(yīng)用 | WB=1:500-2000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 41kDa |
| 細(xì)胞定位 | 細(xì)胞膜 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human LTB4-R2: 25-120/389 <Extracellular> |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
Low-affinity receptor for leukotrienes including leukotriene B4. Mediates chemotaxis of granulocytes and macrophages. The response is mediated via G-proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinities for the leukotrienes is LTB4 > 12-epi-LTB4 > LTB5 > LTB3. Function: Low-affinity receptor for leukotrienes including leukotriene B4. Mediates chemotaxis of granulocytes and macrophages. The response is mediated via G-proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinities for the leukotrienes is LTB4 > 12-epi-LTB4 > LTB5 > LTB3. Subcellular Location: Cell membrane; Multi-pass membrane protein. Tissue Specificity: Widely expressed. Similarity: Belongs to the G-protein coupled receptor 1 family. SWISS: Q9NPC1 Gene ID: 56413 Database links: Entrez Gene: 56413 Human Entrez Gene: 57260 Mouse Omim: 605773 Human SwissProt: Q9NPC1 Human SwissProt: Q9JJL9 Mouse Unigene: 642693 Human Unigene: 657595 Human Unigene: 159670 Mouse Unigene: 485286 Mouse 白三烯B4受體2是白三烯B4受體的新亞型，在炎癥、免疫系統(tǒng)疾病和變態(tài)反應(yīng)、包括一些腫瘤中發(fā)揮著重要作用。 |
| 產(chǎn)品圖片 |
Sample:
Lane 1: Human U937 cell lysates
Lane 2: Human MCF-7 cell lysates
Primary: Anti-LTB4-R2 (bs-2655R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 41 kDa
Observed band size: 41 kDa
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