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Rabbit Anti-TREML1  antibody (bs-2724R)  
~~~促銷代碼KT202411~~~
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產品編號 bs-2724R
英文名稱 Rabbit Anti-TREML1  antibody
中文名稱 髓系細胞觸發(fā)受體樣轉錄因子1抗體
別    名 dJ238O23.3; GLTL1825; MGC119173; PRO3438; TLT 1; TLT1; TREM like transcript 1; Trem like transcript 1 protein; TREML 1; Triggering receptor expressed on myeloid cells like 1; Triggering receptor expressed on myeloid cells like protein 1.   
研究領域 免疫學  淋巴細胞  t-淋巴細胞  b-淋巴細胞  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Mouse (predicted: Human,Rat)
產品應用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 33kDa
細胞定位 細胞漿 細胞膜 細胞外基質 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human TREML1: 201-311/311 <Extracellular>
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 This gene encodes a member of the triggering receptor expressed on myeloid cells-like (TREM) family. The encoded protein is a type 1 single Ig domain orphan receptor localized to the alpha-granule membranes of platelets. The encoded protein is involved in platelet aggregation, inflammation, and cellular activation and has been linked to Gray platelet syndrome. Alternative splicing results in multiple transcript variants [provided by RefSeq, Nov 2012]

Subunit:
When phosphorylated, interacts with PTPN6. When phosphorylated, interacts with PTPN11.

Subcellular Location:
Cell membrane; Single-pass type I membrane protein. Cytoplasm. Note=Sequestered in cytoplasmic vesicles in resting platelets. Transported to the cell surface after stimulation by thrombin. Soluble fragments can be released into the serum by proteolysis.

Tissue Specificity:
Detected in platelets, monocytic leukemia and in T-cell leukemia.

Similarity:
Contains 1 Ig-like V-type (immunoglobulin-like) domain.

SWISS:
Q86YW5

Gene ID:
340205

Database links:

Entrez Gene: 340205 Human

Omim: 609714 Human

SwissProt: Q86YW5 Human

Unigene: 117331 Human



產品圖片
Paraformaldehyde-fixed, paraffin embedded (mouse lymphoid); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (TREML1) Polyclonal Antibody, Unconjugated (bs-2724R) at 1:400 overnight at 4°C, followed by a conjugated secondary (sp-0023) for 20 minutes and DAB staining.
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