吃奶呻吟打开双腿做受动态图 -亚洲色偷偷色噜噜狠狠99网-日韩精品极品视频在线观看免费-来一水AV@lysav

掃碼關(guān)注公眾號           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  人才招聘  關(guān)于我們  聯(lián)系我們
人妻互换一二三区激情视频,偷拍真实夫妇作爱视频,亚洲欧美中文日韩在线V日本
首頁 > 產(chǎn)品中心 > 一抗 > 產(chǎn)品信息
Rabbit Anti-Phospho-MAP3K8 (Ser400)  antibody (bs-3454R)  
~~~促銷代碼KT202411~~~
訂購熱線:400-901-9800
訂購郵箱:sales@xucheq.com
訂購QQ:  400-901-9800
技術(shù)支持:techsupport@xucheq.com
說明書: 50ul  100ul  200ul
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包裝/詢價

產(chǎn)品編號 bs-3454R
英文名稱 Rabbit Anti-Phospho-MAP3K8 (Ser400)  antibody
中文名稱 磷酸化絲裂原活化蛋白激酶激酶8抗體
別    名 MAP3K8 (phospho S400); P-MAP3K8/Tpl2 (Ser400); Phospho-MAP3K8(Ser400); Phospho-Tpl2 (Ser400); P-Tpl2 (Ser400);c COT; Cancer Osaka thyroid oncogene; Cancer Osaka thyroid oncogene; CCOT; COT; COT proto oncogene serine/threonine protein kinase; EST; ESTF; Ewing sarcoma transformant; FLJ10486; M3K8_HUMAN; MAP3K 8; MAP3K8; Mitogen activated protein kinase kinase kinase 8; Mitogen-activated protein kinase kinase kinase 8; Proto oncogene cCot; Proto-oncogene c-Cot; Serine/threonine protein kinase cot; Serine/threonine-protein kinase cot; TPL 2; TPL-2; TPL2; Tumor progression locus 2.  
產(chǎn)品類型 磷酸化抗體 
研究領(lǐng)域 腫瘤  免疫學  信號轉(zhuǎn)導  激酶和磷酸酶  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human,Mouse,Rat (predicted: Rabbit,Pig,Cow,Chicken,Dog,Horse)
產(chǎn)品應(yīng)用 WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,Flow-Cyt=1ug/Test,IF=1:100-500
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 53kDa
細胞定位 細胞漿 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated Synthesised phosphopeptide derived from human MAP3K8/Tpl2 around the phosphorylation site of Ser400: CQ(p-S)LD 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 This gene is an oncogene that encodes a member of the serine/threonine protein kinase family. The encoded protein localizes to the cytoplasm and can activate both the MAP kinase and JNK kinase pathways. This protein was shown to activate IkappaB kinases, and thus induce the nuclear production of NF-kappaB. This protein was also found to promote the production of TNF-alpha and IL-2 during T lymphocyte activation. This gene may also utilize a downstream in-frame translation start codon, and thus produce an isoform containing a shorter N-terminus. The shorter isoform has been shown to display weaker transforming activity. Alternate splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Sep 2011]

Function:
Required for TLR4 activation of the MEK/ERK pathway. Able to activate NF-kappa-B 1 by stimulating proteasome-mediated proteolysis of NF-kappa-B 1/p105. Plays a role in the cell cycle. The longer form has some transforming activity, although it is much weaker than the activated cot oncoprotein.

Subunit:
Forms a ternary complex with NFKB1 and TNIP2.

Subcellular Location:
Cytoplasm.

Tissue Specificity:
Expressed in several normal tissues and human tumor-derived cell lines.

Post-translational modifications:
Autophosphorylated. Isoform 1 undergoes phosphorylation mainly on Ser residues, and isoform 2 on both Ser and Thr residues.

Similarity:
Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.
Contains 1 protein kinase domain.

SWISS:
P41279

Gene ID:
1326

Database links:

Entrez Gene: 1326 Human

Entrez Gene: 26410 Mouse

Entrez Gene: 116596 Rat

Omim: 191195 Human

SwissProt: P41279 Human

SwissProt: Q07174 Mouse

SwissProt: Q63562 Rat

Unigene: 432453 Human

Unigene: 3275 Mouse

Unigene: 9939 Rat



產(chǎn)品圖片
Sample: HepG2(Human) Cell Lysate at 30 ug Primary: Anti-Phospho-MAP3K8 (Ser400) (bs-3454R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 53 kD Observed band size: 53 kD
Sample: RAW264.7(Mouse) Cell Lysate at 30 ug Primary: Anti-Phospho-MAP3K8 (Ser400) (bs-3454R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 53 kD Observed band size: 53 kD
Sample: Spleen (Mouse) Lysate at 40 ug Primary: Anti-Phospho-MAP3K8 (Ser400) (bs-3454R) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 53 kD Observed band size: 55 kD
Paraformaldehyde-fixed, paraffin embedded (Rat brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (Phospho-MAP3K8 (Ser400)) Polyclonal Antibody, Unconjugated (bs-3454R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
Blank control: Hela. Primary Antibody (green line): Rabbit Anti-MAP3K8 antibody (bs-3454R) Dilution: 1μg /10^6 cells; Isotype Control Antibody (orange line): Rabbit IgG . Secondary Antibody : Goat anti-rabbit IgG-PE Dilution: 1μg /test. Protocol The cells were fixed with 4% PFA (10min at room temperature)and then permeabilized with PBST for 20 min at room temperature. The cells were then incubated in 5%BSA to block non-specific protein-protein interactions for 30 min at at room temperature .Cells stained with Primary Antibody for 30 min at room temperature. The secondary antibody used for 40 min at room temperature. Acquisition of 20,000 events was performed.
版權(quán)所有 2004-2026 www.xucheq.com 北京博奧森生物技術(shù)有限公司
通過國際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網(wǎng)安備110107000727號
高潮VPSWINDOWS国产乱| 国产chinesehdxxxx| 被黑人猛躁10次高潮视频| 亚洲精品亚洲人成人网| BGMBGMBGM毛多多视频| 无码人妻精品一区二区三区66| 亚洲VA国产VA天堂VA久久| 大又大粗又爽又黄少妇毛片| 无码一区二区三区在线观看| 亚婷婷洲AV久久蜜臀无码| 午夜精品久久久久久久久| 香蕉久久精品日日躁夜夜躁| 扒开腿狂躁女人爽出白浆| 年轻的母亲在线| 亚洲AV在线观看| 亚洲国产精品无码| 日本三级欧美三级人妇视频黑白配 | 69SEX久久精品国产麻豆| 久久亚洲AV成人无码国产| 国产手机精品一区二区| 亚洲国产婷婷香蕉久久久久久| 图片区小说区激情区偷拍区| 国产精品99久久久久久WWW| 亚洲精品无码午夜福利中文字幕| 裸身美女无遮挡永久免费视频 | 网站你懂得| 中字幕视频在线永久在线观看免费 | 亚洲精品久久无码AV片俺去也| 日韩精品人妻系列无码专区免费| 永久免费看A片无码网站宅男| 亚洲精品国产精品乱码视色| 国产精品免费看久久久无码| 日本VA欧美VA欧美VA精品| 无码人妻精品一区二区三区不卡 | 亚洲精品无码午夜福利中文字幕 | 无码88AⅤ欧美熟妇人妻影院 | 亚洲AV永久无码精品古装片| 久久精品国产精品亚洲毛片| 免费观看少妇全黄A片| 中文字幕人妻女友一区蜜芽视频| 亚洲AV无码久久寂寞少妇|