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Rabbit Anti-SLCO2B1  antibody (bs-3913R)  
~~~促銷代碼KT202411~~~
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產(chǎn)品編號(hào) bs-3913R
英文名稱 Rabbit Anti-SLCO2B1  antibody
中文名稱 可溶性載質(zhì)轉(zhuǎn)運(yùn)蛋白2B1抗體
別    名 Moat 1; Moat1; Multispecific organic anion transporter 1; Multispecific organic anion transporter1; OATP 2B1; OATP B; OATP RP2; OATP2 B1; OATP2B1; OATPB; OATPRP 2; OATPRP2; Organic anion transporter B; Organic anion transporter polypeptide related protein 2; Organic anion transporter polypeptide related protein2; SLC 21A9; SLC2 1A9; SLC21 A9; SLC21A9; SLCO 2B1; SLCO2 B1; SO 2B1; SO2 B1; SO2B1; Solute carrier family 21 (organic anion transporter), member 9; Solute carrier family 21 member 9; Solute carrier organic anion transporter family member 2B1; SO2B1_HUMAN.  
Specific References  (2)     |     bs-3913R has been referenced in 2 publications.
[IF=10.334] Wenlong Li. et al. Organic anion-transporting polypeptide 2B1 knockout and humanized mice; insights into the handling of bilirubin and drugs. PHARMACOL RES. 2023 Mar;:106724  IHC ;  Mouse.  
[IF=3.84] Yamamoto, Kotaro, et al. "The neuroprotective effect of latanoprost acts via klotho‐mediated suppression of calpain activation after optic nerve transection." Journal of Neurochemistry (2016).  IHC-F ;  Rat.  
研究領(lǐng)域 腫瘤  細(xì)胞生物  免疫學(xué)  轉(zhuǎn)錄調(diào)節(jié)因子  轉(zhuǎn)運(yùn)蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human,Mouse,Rat (predicted: Rabbit,Cow,Dog,Horse)
產(chǎn)品應(yīng)用 WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 77kDa
細(xì)胞定位 細(xì)胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human SLCO2B1: 531-630/709 <Cytoplasmic>
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項(xiàng) This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 SLCO2B1 (solute carrier organic anion transporter family member 2B1), or Organic anion transporter B (OATP-B) mediates sodium-independent transport of organic anions. Unlike other related proteins, SLCO2B1 is expressed in many tissues, including liver, placenta, brain, heart and intestine. SLCO2B1 plays a role in the uptake of steroids and a number of drugs such as statins.

Function:
Mediates the Na(+)-independent transport of organic anions such as taurocholate, the prostaglandins PGD2, PGE1, PGE2, leukotriene C4, thromboxane B2 and iloprost.

Subcellular Location:
Cell membrane; Multi-pass membrane protein.

Similarity:
Belongs to the organo anion transporter (TC 2.A.60) family.
Contains 1 Kazal-like domain.

SWISS:
O94956

Gene ID:
11309

Database links:

Entrez Gene: 11309 Human

Entrez Gene: 101488 Mouse

Entrez Gene: 140860 Rat

Omim: 604988 Human

SwissProt: O94956 Human

SwissProt: Q8BXB6 Mouse

SwissProt: Q9JHI3 Rat

Unigene: 7884 Human

Unigene: 11249 Mouse

Unigene: 44538 Rat



OATPRP2又稱陰離子轉(zhuǎn)運(yùn)蛋白家族2B1、有機(jī)陰離子轉(zhuǎn)運(yùn)多肽相關(guān)蛋白2。
產(chǎn)品圖片
Sample: Cerebrum (Mouse) Lysate at 40 ug Cerebrum (Rat) Lysate at 40 ug Primary: Anti- SLCO2B1 (bs-3913R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 77 kD Observed band size: 87 kD
Tissue/cell: rat brain tissue; 4% Paraformaldehyde-fixed and paraffin-embedded; Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,C-0005) at 37℃ for 20 min; Incubation: Anti-SLCO2B1 Polyclonal Antibody, Unconjugated(bs-3913R) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody(SP-0023) and DAB(C-0010) staining
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