產(chǎn)品編號(hào) | bs-0057P |
英文名稱 | Amylin Antibody Blocking Peptide |
中文名稱 | 糖尿病相關(guān)肽/胰島淀粉樣肽封閉多肽 |
別 名 | Islet amyloid polypeptide; IAPP; DAP; Diabetes associated peptide; IAP; Insulinoma amyloid peptide. |
性 狀 | Lyophilized |
物 種 | human |
純化方法 | 1 |
活性 | Yes |
保存條件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
產(chǎn)品介紹 |
Amylin is commonly found in pancreatic islets of patients suffering diabetes mellitus type II, or harboring an insulinoma. While the assosciation of amylin with the development of type II diabetes has been known for some time, a direct causative role for amylin has been harder to establish. Recent results suggest that amylin, like the related beta amyloid (Abeta) assosciated with Alzheimer's disease, can induce apoptotic cell death in particular cultured cells, an effect that may be relevant to the development of type II diabetes. SWISS: P10997 Gene ID: 3375 胰島淀粉樣肽(islet amyloid polypeptide,IAPP)又稱amylin 或糖尿病相關(guān)肽是由胰腺β細(xì)胞產(chǎn)生的一種短肽。IAPP降低胰島素的敏感性,抑制肌肉組織中葡萄糖的攝取和糖原的合成,抑制病人攝取食物 |