| 產(chǎn)品編號 | bs-5918R |
| 英文名稱 | Rabbit Anti-ANGPTL3 antibody |
| 中文名稱 | 血管生成素樣蛋白3抗體 |
| 別 名 | ANG 5; ANG-5; ANG5; Angiopoietin 5; Angiopoietin like 3; Angiopoietin related protein 3; Angiopoietin-5; Angiopoietin-like protein 3; Angiopoietin-related protein 3; ANGL3_HUMAN; ANGPT5; FHBL2. |
| 研究領(lǐng)域 | 腫瘤 心血管 細(xì)胞生物 免疫學(xué) 信號轉(zhuǎn)導(dǎo) 生長因子和激素 血管內(nèi)皮細(xì)胞 新陳代謝 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | Human |
| 產(chǎn)品應(yīng)用 | WB=1:500-2000,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 49kDa |
| 細(xì)胞定位 | 分泌型蛋白 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human ANG5/ANGPTL3: 51-150/460 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
Angiopoietin-like protein 3 (Angptl3) functions as a potent lipoprotein lipase inhibitor and is an important component of plasma triglyceride homeostasis. Angptl3 also plays a role in adipose formation and angiogenesis through its interaction with integrin ?v)beta(3). It is secreted by the liver and is functionally defined by the C-terminal fibrinogen (FBN)-like domain and an N-terminal coiled-coil domain. Angptl3 regulates circulating triglyceride levels during different nutritional states thereby mediating the feeding/fasting cycle. A deficiency of Angptl3 results in abnormally low lipid levels, and a repression of the protein may be protective against atherosclerosis. Angptl3 may also play an important role in hyperlipidemia in diabetes. Subcellular Location: Secreted Tissue Specificity: Expressed principally in liver. Weakly expressed in kidney. Similarity: Contains 1 fibrinogen C-terminal domain. SWISS: Q9Y5C1 Gene ID: 27329 Database links: Entrez Gene: 27329 Human Entrez Gene: 30924 Mouse Omim: 604774 Human SwissProt: Q9Y5C1 Human SwissProt: Q9R182 Mouse Unigene: 209153 Human Unigene: 28341 Mouse |
| 產(chǎn)品圖片 |
Sample:
Hepg2(Human) Cell Lysate at 30 ug
Primary: Anti-ANGPTL3 (bs-5918R) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 49 kD
Observed band size: 59 kD
Sample:
Lane 1: Human HL-60 cell Lysates
Lane 2: Human HepG2 cell Lysates
Lane 3: Human 293T cell Lysates
Lane 4: Human Raji cell Lysates
Lane 5: Human MOLT4 cell Lysates
Primary: Anti-ANGPTL3 (bs-5918R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 49kDa
Observed band size: 60kDa
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