| 產(chǎn)品編號(hào) | bs-5773R |
| 英文名稱 | Rabbit Anti-FGF22 antibody |
| 中文名稱 | 成纖維細(xì)胞生長(zhǎng)因子22抗體 |
| 別 名 | FGF 22; FGF-22; FGF22; FGF22_HUMAN; Fibroblast growth factor 22; si:dkey 21e2.2. |
| 研究領(lǐng)域 | 腫瘤 心血管 免疫學(xué) 信號(hào)轉(zhuǎn)導(dǎo) 生長(zhǎng)因子和激素 |
| 抗體來(lái)源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human,Mouse,Cow) |
| 產(chǎn)品應(yīng)用 | WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 17kDa |
| 細(xì)胞定位 | 分泌型蛋白 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human FGF22.: 23-100/170 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
FGF22 is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. The mouse homolog of this gene was found to be preferentially expressed in the inner root sheath of the hair follicle, which suggested a role in hair development.
Fibroblast Growth Factor-22 stimulates the proliferation and activation of cells that express FGF receptor. Function: Plays a role in the fasting response, glucose homeostasis, lipolysis and lipogenesis. Can stimulate cell proliferation (in vitro). May be involved in hair development. Subunit: Interacts with FGFR1 and FGFR2. Interacts with FGFBP1. Subcellular Location: Secreted (Potential). Similarity: Belongs to the heparin-binding growth factors family. SWISS: Q9HCT0 Gene ID: 27006 Database links: Entrez Gene: 27006 Human Entrez Gene: 67112 Mouse Omim: 605831 Human SwissProt: Q9HCT0 Human SwissProt: Q9ESS2 Mouse Unigene: 248087 Human Unigene: 154211 Mouse Unigene: 198777 Rat |
