產(chǎn)品編號(hào) | bs-5916R |
英文名稱 | Rabbit Anti-Annexin A9 antibody |
中文名稱 | 膜粘連蛋白9抗體 |
別 名 | annexin 31; annexin A9; annexin XXXI; ANX31; ANXA9; ANXA 9; ANXA-9; pemphaxin; ANXA9_HUMAN . |
研究領(lǐng)域 | 細(xì)胞生物 免疫學(xué) 細(xì)胞粘附分子 |
抗體來(lái)源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | (predicted: Human,Mouse,Rat,Pig,Cow,Dog,Horse) |
產(chǎn)品應(yīng)用 | WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理論分子量 | 38kDa |
細(xì)胞定位 | 細(xì)胞漿 細(xì)胞外基質(zhì) 分泌型蛋白 |
性 狀 | Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human Annexin A9: 261-345/345 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
產(chǎn)品介紹 |
ANXA9 may act as a low affinity receptor for acetylcholine and is expressed in the stratified squamous skin epithelium, but not in epithelia of other types (at protein level). ANXA9 is one of the target molecules recognized by autoantibodies in patients with pemphigus vulgaris, a rare, autoimmune skin disease in which epidermal blisters occur as the result of the loss of cell-cell adhesion. Function: Low affinity receptor for acetylcholine known to be targeted by disease-causing pemphigus vulgaris antibodies in keratinocytes. Subunit: Homodimer. Tissue Specificity: Expressed in the stratified squamous skin epithelium, but not in epithelia of other types (at protein level). Similarity: Belongs to the annexin family. Contains 4 annexin repeats. SWISS: O76027 Gene ID: 8416 Database links: Entrez Gene: 8416 Human Entrez Gene: 71790 Mouse Omim: 603319 Human SwissProt: O76027 Human SwissProt: Q9JHQ0 Mouse Unigene: 3346 Human Unigene: 218844 Mouse |