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Rabbit Anti-CST7  antibody (bs-6039R)  
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產(chǎn)品編號 bs-6039R
英文名稱 Rabbit Anti-CST7  antibody
中文名稱 半胱氨酸蛋白酶抑制劑7抗體
別    名 CMAP; CST 7; CST7; Cystatin 7; Cystatin-7; Cystatin7; Cystatin like metastasis associated protein; CystatinF; Cystatin-F; Cystatin F; Leukocystatin.  
Specific References  (1)     |     bs-6039R has been referenced in 1 publications.
[IF=15.6] Zhang, L., Liu, X., Liu, D., Yu, X., Zhang, L., Zhu, J., … Liu, R. (2020). A Conditionally Releasable “Do not Eat Me” CD47 Signal Facilitates Microglia‐Targeted Drug Delivery for the Treatment of Alzheimer’s Disease. Advanced Functional Materials, 1910691.  WB ;  mouse.  
研究領(lǐng)域 心血管  細胞生物  免疫學(xué)  信號轉(zhuǎn)導(dǎo)  細胞凋亡  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human,Mouse,Rat)
產(chǎn)品應(yīng)用 WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 14kDa
細胞定位 細胞漿 分泌型蛋白 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Cystatin F: 21-120/145 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions. Expression of the protein has been observed in various human cancer cell lines established from malignant tumors.

Function:
Inhibits papain and cathepsin L but with affinities lower than other cystatins. May play a role in immune regulation through inhibition of a unique target in the hematopoietic system.

Subunit:
Homodimer; disulfide-linked.

Subcellular Location:
Secreted. Cytoplasm.

Tissue Specificity:
Primarily expressed in peripheral blood cells and spleen.

Similarity:
Belongs to the cystatin family.

SWISS:
O76096

Gene ID:
8530

Database links:

Entrez Gene: 8530 Human

Omim: 603253 Human

SwissProt: O76096 Human

Unigene: 143212 Human



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