| 產(chǎn)品編號 | bs-6297R |
| 英文名稱 | Rabbit Anti-HLC3/Kanadaptin antibody |
| 中文名稱 | 肺癌癌基因蛋白3抗體 |
| 別 名 | HLC3; HLC-3; Human lung cancer oncogene 3 protein; Kanadaptin; Kidney anion exchanger adapter protein; Kidney anion exchanger adaptor protein; Lung cancer oncogene 3 protein; NADAP_HUMAN; SLC4A1AP; Solute carrier family 4 (anion exchanger) member 1 adaptor protein; Solute carrier family 4 anion exchanger member 1 adapter protein. |
| 研究領(lǐng)域 | 腫瘤 心血管 細(xì)胞生物 腫瘤細(xì)胞生物標(biāo)志物 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human,Mouse,Rat,Pig,Sheep,Cow,Chicken,Dog,Horse) |
| 產(chǎn)品應(yīng)用 | WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 89kDa |
| 細(xì)胞定位 | 細(xì)胞核 細(xì)胞漿 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human Kanadaptin: 401-500/796 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
HLC-3 is a 796 amino acid protein that is widely expressed in many tissues, including kidney, lung, liver, brain and skeletal and cardiac muscle. SLC4A1AP is a multidomain protein that localizes to the nucleus where it may play a role in signaling. SLC4A1AP was previously thought to act as an adaptor protein or chaperone involved in targeting kAE1 to the plasma membrane. However, recent studies suggest SLC4A1AP does not interact with kAE1. The gene encoding SLC4A1AP maps to chromosome 2, which consists of 237 million bases and makes up approximately 8% of the human genome. A number of genetic diseases are linked to genes on chromosome 2, including Harlequin icthyosis, sitosterolemia and Alstr鰉 syndrome. Subcellular Location: Nucleus. Cytoplasm. Mainly nuclear. Small amounts are found in the cytoplasm. Tissue Specificity: Ubiquitously expressed. Similarity: Contains 1 FHA domain. SWISS: Q9BWU0 Gene ID: 22950 Database links: Entrez Gene: 22950 Human Entrez Gene: 20534 Mouse Omim: 602655 Human SwissProt: Q9BWU0 Human Unigene: 306000 Human Unigene: 352407 Mouse |
