吃奶呻吟打开双腿做受动态图 -亚洲色偷偷色噜噜狠狠99网-日韩精品极品视频在线观看免费-来一水AV@lysav

掃碼關(guān)注公眾號(hào)           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  人才招聘  關(guān)于我們  聯(lián)系我們
韩国午夜理伦三级在线观看中文版 ,好深好湿好硬顶到了好爽
首頁(yè) > 產(chǎn)品中心 > 一抗 > 產(chǎn)品信息
Rabbit Anti-Frizzled 2  antibody (bs-6623R)  
~~~促銷代碼KT202411~~~
訂購(gòu)熱線:400-901-9800
訂購(gòu)郵箱:sales@xucheq.com
訂購(gòu)QQ:  400-901-9800
技術(shù)支持:techsupport@xucheq.com
說(shuō)明書(shū): 50ul  100ul  200ul
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包裝/詢價(jià)

產(chǎn)品編號(hào) bs-6623R
英文名稱 Rabbit Anti-Frizzled 2  antibody
中文名稱 Wnt信號(hào)受體FZD2蛋白抗體
別    名 Frizzled homolog 2; Frizzled-2; Frizzled2; Fz 2; Fz-2; Fz2; FZD 2; FZD2; FZD2_HUMAN; FzE 2; FzE2; hFz 2; hFz2.  
研究領(lǐng)域 腫瘤  細(xì)胞生物  信號(hào)轉(zhuǎn)導(dǎo)  干細(xì)胞  轉(zhuǎn)錄調(diào)節(jié)因子  G蛋白偶聯(lián)受體  細(xì)胞表面分子  G蛋白信號(hào)  
抗體來(lái)源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Mouse,Rat (predicted: Human,Rabbit,Pig,Sheep,Cow,Dog,Goat)
產(chǎn)品應(yīng)用 WB=1:500-2000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 60kDa
細(xì)胞定位 細(xì)胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Frizzled 2: 61-160/565 <Extracellular>
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項(xiàng) This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 The frizzled gene, originally identified in Drosophila melanogaster, is involved in the development of tissue polarity. The mammalian homolog of frizzled as well as several secreted mammalian frizzled-related proteins (FRPs) have been described. The frizzled proteins contain seven transmembrane domains, a cysteine-rich domain in the extracellular region and a carboxy terminal Ser/Thr-xxx-Val motif. They function as receptors for Wnt and are generally coupled to G proteins. Expression of frizzled-2 can be observed in the fetal kidney and lung and in the adult ovary and colon. The Wnt/cGMP/Ca2+ pathway is mediated by frizzled-2 . It binds Wnt proteins and signals by activating the release of stored calcium. Expression of frizzled-2 is regulated by Angiotensin II. Activated frizzled-2 suppresses the activity of protein kinase G, and activates NFAT-dependent transcription, the phosphatidylinositol pathway and calcium sensitive enzymes.

Function:
Receptor for Wnt proteins. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase. Both pathways seem to involve interactions with G-proteins. May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues.

Subcellular Location:
Membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.

Tissue Specificity:
Widely expressed. In the adult, mainly found in heart, placenta, skeletal muscle, lung, kidney, pancreas, prostate, testis, ovary and colon. In the fetus, expressed in brain, lung and kidney. Low levels in fetal liver.

Post-translational modifications:
Ubiquitinated by ZNRF3, leading to its degradation by the proteasome (By similarity).

Similarity:
Belongs to the G-protein coupled receptor Fz/Smo family.
Contains 1 FZ (frizzled) domain.

SWISS:
Q14332

Gene ID:
2535

Database links:

Entrez Gene: 2535 Human

Entrez Gene: 57265 Mouse

Entrez Gene: 64512 Rat

Omim: 600667 Human

SwissProt: Q14332 Human

SwissProt: Q9JIP6 Mouse

SwissProt: Q08464 Rat

Unigene: 142912 Human

Unigene: 597264 Human

Unigene: 36416 Mouse

Unigene: 92324 Rat



產(chǎn)品圖片
Sample: Placenta (Mouse) Lysate at 40 ug Primary: Anti-Frizzled 2 (bs-6623R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 60 kD Observed band size: 60 kD
版權(quán)所有 2004-2026 www.xucheq.com 北京博奧森生物技術(shù)有限公司
通過(guò)國(guó)際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書(shū)編號(hào): 00124Q34771R2M/1100
通過(guò)國(guó)際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書(shū)編號(hào): CQC24QY10047R0M/1100
京ICP備05066980號(hào)-1         京公網(wǎng)安備110107000727號(hào)
国产成人无码A区在线观看视频| 国产精品久久777777| 老旺的大肉蟒进进出出| 特级毛片爽WWW免费版| 国产一区二区在线视频| 欧美激情综合五月色丁香| 搡BBBB搡BBB搡| 又粗又大内射免费视频小说| 最近免费中文字幕MV在线视频3| 公交车被两根粗大同进同出| 最近免费中文字幕中文高清百度| 国产AV一区二区三区| 国产免费视频| 久久夜色精品国产噜噜麻豆| 4444亚洲人成无码网在线观看 | 国产精品 高清 尿 小便 嘘嘘| 最近中文字幕在线看免费完整版 | 欧美黑人添添高潮A片WWW| АⅤ天堂中文在线网| 少妇又色又紧又爽又刺激视频| 久久AV喷潮久久AV高清| 国产SUV精二区69| 最近中文字幕在线看免费完整版| 中文字幕一区二区三区乱码| 亚洲无AV在线中文字幕| 久久精品中文字幕| EEUSS鲁丝片AV无码| 亚洲精品久久无码| 亚洲精品久久久久久一区二区| H动漫在线观看| 久久久久99人妻一区二区三区| 亚洲精华国产精华精华液网站| 亚洲女人被黑人巨大进入| 午夜欧美精品久久久久久久| 日韩精品极品视频在线观看免费| 久久 国产 尿 小便 嘘嘘 | 肉乳乱无码A片观看免费| 久久久久亚洲精品无码蜜桃| 亚洲精品乱码久久久久久不卡| 中文字幕AV久久一区二区| 老师穿着旗袍肉色丝袜让我玩|