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Rabbit Anti-SOX11  antibody (bs-6736R)  
~~~促銷代碼KT202411~~~
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200ul/2800.00元
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產(chǎn)品編號(hào) bs-6736R
英文名稱 Rabbit Anti-SOX11  antibody
中文名稱 轉(zhuǎn)錄因子SOX-11蛋白抗體
別    名 SRY (sex determining region Y) box 11; SRY related HMG box gene 11; Transcription factor SOX-11; SOX11_HUMAN.  
研究領(lǐng)域 腫瘤  細(xì)胞生物  神經(jīng)生物學(xué)  信號(hào)轉(zhuǎn)導(dǎo)  干細(xì)胞  轉(zhuǎn)錄調(diào)節(jié)因子  表觀遺傳學(xué)  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human,Mouse (predicted: Rat,Rabbit,Pig,Cow)
產(chǎn)品應(yīng)用 WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 47kDa
細(xì)胞定位 細(xì)胞核 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human SOX11: 51-150/441 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項(xiàng) This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 This intronless gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. The protein may function in the developing nervous system and play a role in tumorigenesis. [provided by RefSeq, Jul 2008]

Function:
Transcriptional activator.

Subcellular Location:
Nucleus.

Tissue Specificity:
Mainly expressed in the developing central nervous system.

Similarity:
Contains 1 HMG box DNA-binding domain.

SWISS:
P35716

Gene ID:
6664

Database links:

Entrez Gene: 6664 Human

Entrez Gene: 20666 Mouse

Entrez Gene: 84046 Rat

Omim: 600898 Human

SwissProt: P35716 Human

SwissProt: Q7M6Y2 Mouse

SwissProt: P0C1G9 Rat

Unigene: 432638 Human

Unigene: 41702 Mouse

Unigene: 466344 Mouse

Unigene: 162854 Rat



產(chǎn)品圖片
25 ug total protein per lane of various lysates (see on figure) probed with SOX11 polyclonal antibody, unconjugated (bs-6736R) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r.t. for 60 min.
Paraformaldehyde-fixed, paraffin embedded (Human breast carcinoma); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (SOX11) Polyclonal Antibody, Unconjugated (bs-6736R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
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