產(chǎn)品編號(hào) | bs-4687R |
英文名稱 | Rabbit Anti-AMH antibody |
中文名稱 | Muellerian繆勒管激素抑制因子抗體 |
別 名 | MIS_HUMAN; Anti muellerian hormone; MIF; MIS; Muellerian inhibiting factor; Mullerian inhibiting substance; Muellerian-inhibiting factor; Anti-Muellerian hormone; AMH; Muellerian-inhibiting substance. |
Specific References (4) | bs-4687R has been referenced in 4 publications.
[IF=11.459] Su Zhouet al. Ovarian Dysfunction Induced by Chronic Whole‐Body PM2.5 Exposure. Small
. 2020 Aug;16(33):e2000845. ELISA ; mouse.
[IF=6.183] Shan Zhang. et al. Early evaluation of survival of the transplanted ovaries through ultrasound molecular imaging via targeted nanobubbles. Biomater Sci-Uk. 2020 Sep;8(19):5402-5414 WB,IF ; Rat.
[IF=4.384] Jiao-jiao ZHANG. et al. Cold plasma promotes Sertoli cell proliferation via AMPK-mTOR signaling pathway1. J INTEGR AGR. 2022 Jul;: IF ; Chicken.
[IF=2.984] Wang W et al. Amh dominant expression in Sertoli cells during the testicular differentiation and development stages in the olive flounder Paralichthys olivaceus. Gene
. 2020 Sep 10;755:144906. IHC ; flounder.
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研究領(lǐng)域 | 腫瘤 細(xì)胞生物 發(fā)育生物學(xué) 信號(hào)轉(zhuǎn)導(dǎo) 干細(xì)胞 生長(zhǎng)因子和激素 轉(zhuǎn)錄調(diào)節(jié)因子 |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | Human (predicted: Mouse,Rat,Pig,Cow,Dog,Horse) |
產(chǎn)品應(yīng)用 | WB=1:500-2000,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理論分子量 | 57kDa |
細(xì)胞定位 | 分泌型蛋白 |
性 狀 | Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human AMH: 501-560/560 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
產(chǎn)品介紹 |
Anti-Mullerian hormone is a member of the transforming growth factor-beta gene family which mediates male sexual differentiation. Anti-Mullerian hormone causes the regression of Mullerian ducts which would otherwise differentiate into the uterus and fallopian tubes. Some mutations in the anti-Mullerian hormone result in persistent Mullerian duct syndrome. [provided by RefSeq, Jul 2008]. Function: This glycoprotein, produced by the Sertoli cells of the testis, causes regression of the Muellerian duct. It is also able to inhibit the growth of tumors derived from tissues of Muellerian duct origin. Subunit: Homodimer; disulfide-linked. Subcellular Location: Secreted. DISEASE: Persistent Muellerian duct syndrome 1 (PMDS1) [MIM:261550]: A form of male pseudohermaphroditism characterized by a failure of Muellerian duct regression in otherwise normal males. Note=The disease is caused by mutations affecting the gene represented in this entry. Similarity: Belongs to the TGF-beta family. SWISS: P03971 Gene ID: 268 Database links: Entrez Gene: 268 Human Entrez Gene: 11705 Mouse Omim: 600957 Human SwissProt: P03971 Human SwissProt: P27106 Mouse Unigene: 112432 Human Unigene: 19121 Rat |