產(chǎn)品編號(hào) | bs-8166R |
英文名稱 | Rabbit Anti-COX5A antibody |
中文名稱 | 細(xì)胞色素c氧化酶5A抗體 |
別 名 | COX; COX VA; COX5A; COX5A_HUMAN; Cytochrome c oxidase polypeptide Va; Cytochrome c oxidase polypeptide, mitochondrial; Cytochrome c oxidase subunit 5A; Cytochrome c oxidase subunit 5A, mitochondrial; mitochondrial; Mitochondrial cytochrome c oxidase subunit Va; VA. |
研究領(lǐng)域 | 細(xì)胞生物 免疫學(xué) 線粒體 |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | (predicted: Human,Mouse,Rat,Chicken,Horse) |
產(chǎn)品應(yīng)用 | WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理論分子量 | 12kDa |
細(xì)胞定位 | 細(xì)胞漿 細(xì)胞膜 線粒體 |
性 狀 | Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human COX5A: 41-150/150 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
產(chǎn)品介紹 |
Cytochrome c oxidase (COX) is the terminal enzyme of the mitochondrial respiratory chain. It is a multi-subunit enzyme complex that couples the transfer of electrons from cytochrome c to molecular oxygen and contributes to a proton electrochemical gradient across the inner mitochondrial membrane. The complex consists of 13 mitochondrial- and nuclear-encoded subunits. The mitochondrially-encoded subunits perform the electron transfer of proton pumping activities. The functions of the nuclear-encoded subunits are unknown but they may play a role in the regulation and assembly of the complex. This gene encodes the nuclear-encoded subunit Va of the human mitochondrial respiratory chain enzyme. A pseudogene COX5AP1 has been found in chromosome 14q22. [provided by RefSeq, Jul 2008]. Function: This is the heme A-containing chain of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport. Subcellular Location: Mitochondrion inner membrane. Similarity: Belongs to the cytochrome c oxidase subunit 5A family. SWISS: P20674 Gene ID: 9377 Database links: Entrez Gene: 9377 Human Entrez Gene: 12858 Mouse Omim: 603773 Human SwissProt: P20674 Human SwissProt: P12787 Mouse Unigene: 401903 Human Unigene: 273403 Mouse Unigene: 11077 Rat |