產(chǎn)品編號(hào) | bs-9345R |
英文名稱 | Rabbit Anti-MARCH11 antibody |
中文名稱 | 膜相關(guān)環(huán)指蛋白11抗體 |
別 名 | E3 ubiquitin-protein ligase MARCH11; MARCH-XI; March11; MARHB_HUMAN; Membrane associated ring finger (C3HC4) 11; Membrane-associated RING finger protein 11; Membrane-associated RING-CH protein XI. |
研究領(lǐng)域 | 細(xì)胞生物 免疫學(xué) 通道蛋白 表觀遺傳學(xué) |
抗體來(lái)源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | Human (predicted: Mouse,Rat,Sheep,Cow,Dog,Horse) |
產(chǎn)品應(yīng)用 | WB=1:500-2000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理論分子量 | 44kDa |
細(xì)胞定位 | 細(xì)胞漿 細(xì)胞膜 |
性 狀 | Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human MARCH11: 301-400/402 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
產(chǎn)品介紹 |
E3 ubiquitin-protein ligase that mediates polyubiquitination of CD4. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates. May play a role in ubuquitin-dependent protein sorting in developmenting spermatids. Function: E3 ubiquitin-protein ligase that mediates polyubiquitination of CD4. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates. May play a role in ubuquitin-dependent protein sorting in developmenting spermatids (By similarity). Subunit: Interacts (YXXL motif) with AP1M1. Interacts (via PDZ-binding motif) with LIN7A. Interacts with unidentified fucose glycoproteins (By similarity). Subcellular Location: Cytoplasmic vesicle membrane; Multi-pass membrane protein (By similarity). Similarity: Contains 1 RING-CH-type zinc finger. SWISS: A6NNE9 Gene ID: 441061 Database links: Entrez Gene: 441061 Human Omim: 613338 Human SwissProt: A6NNE9 Human Unigene: 662216 Human |
產(chǎn)品圖片 | |