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Rabbit Anti-Kinesin/KIF5B  antibody (bs-11026R)  
~~~促銷代碼KT202411~~~
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產(chǎn)品編號 bs-11026R
英文名稱 Rabbit Anti-Kinesin/KIF5B  antibody
中文名稱 驅(qū)動(dòng)蛋白KNS1抗體
別    名 Conventional kinesin heavy chain; KIF5B; Kinesin 1 (110-120kD); Kinesin family member 5B; Kinesin heavy chain; Kinesin heavy chain ubiquitous; Kinesin-1 heavy chain; KINH; KINH_HUMAN; KNS 1; KNS; KNS1; Ubiquitous kinesin heavy chain; UKHC.  
研究領(lǐng)域 神經(jīng)生物學(xué)  信號轉(zhuǎn)導(dǎo)  細(xì)胞粘附分子  細(xì)胞骨架  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human (predicted: Mouse,Rat,Rabbit,Pig,Cow,Chicken,Horse)
產(chǎn)品應(yīng)用 Flow-Cyt=1μg/Test
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 106kDa
細(xì)胞定位 細(xì)胞漿 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Kinesin: 561-660/963 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項(xiàng) This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 Structural proteins in Arabidopsis provide cellular stability, facilitate protein transportation within the cell and are essential for cell growth. Three types of molecular motors are involved in the organization, dynamics and transport processes associated with the cytoskeleton (1). They include myosin, which transports cargo along actin filaments, and kinesin and dynein, which transport cargo along microtubules (1,2). These proteins regulate many cellular functions, including cell division and expansion, cell-to-cell communication, membrane trafficking and morphogenesis (2). In addition, the dynamin-like proteins are GTP-binding proteins involved in vesicle trafficking (3). Extensin is a structural protein that may be involved in cell wall assembly, while expansin is a cell wall loosening protein that induces stress relaxation and extension of cell walls and may control organ size, morphology and abscission (4,5). Also, xyloglucan (XG), a major hemicellulose in plants, is modified by the fucosyltransferase, XG FTase, which adds a terminal fucosyl residue to XG (6).

Function:
Microtubule-dependent motor required for normal distribution of mitochondria and lysosomes.

Subunit:
Oligomer composed of two heavy chains and two light chains. Interacts with GRIP1 and PPP1R42 (By similarity). Interacts with SYBU. Interacts with JAKMIP1. Interacts with PLEKHM2. Interacts with ECM29.

Subcellular Location:
Cytoplasm, cytoskeleton. Note=Uniformly distributed between soma and neurites in hippocampal neurons.

Similarity:
Belongs to the kinesin-like protein family. Kinesin subfamily.
Contains 1 kinesin-motor domain.

SWISS:
P33176

Gene ID:
3799

Database links:

Entrez Gene: 3799 Human

Entrez Gene: 16573 Mouse

Entrez Gene: 117550 Rat

Omim: 602809 Human

SwissProt: P33176 Human

SwissProt: Q61768 Mouse

SwissProt: Q2PQA9 Rat

Unigene: 327736 Human

Unigene: 644646 Human

Unigene: 223744 Mouse

Unigene: 4046 Rat



產(chǎn)品圖片
Blank control(blue): Hela(fixed with 2% paraformaldehyde (10 min) and then permeabilized with ice-cold 90% methanol for 30 min on ice). Primary Antibody: Rabbit Anti-KinesinKIF5B/FITC Conjugated antibody (bs-11026R /FITC), Dilution: 1μg in 100 μL 1X PBS containing 0.5% BSA; Isotype Control Antibody: Rabbit IgG/FITC(orange) ,used under the same conditions.
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