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Rabbit Anti-Bestrophin 3  antibody (bs-11042R)  
~~~促銷代碼KT202411~~~
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說明書: 50ul  100ul  200ul
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包裝/詢價(jià)
產(chǎn)品編號 bs-11042R
英文名稱 Rabbit Anti-Bestrophin 3  antibody
中文名稱 卵黃狀黃斑病蛋白3抗體
別    名 Vitelliform macular dystrophy 2 like protein 3; BEST 3; BEST3; BEST3_HUMAN; Bestrophin-3; Bestrophin3; Vitelliform macular dystrophy 2 like 3; Vitelliform macular dystrophy 2-like protein 3; VMD2L3.  
研究領(lǐng)域 腫瘤  信號轉(zhuǎn)導(dǎo)  通道蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human,Mouse,Rat,Pig,Dog,Horse)
產(chǎn)品應(yīng)用 WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 76kDa
細(xì)胞定位 細(xì)胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Bestrophin 3: 45-92/668 <Extracellular>
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項(xiàng) This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 Bestrophin-3 is a 668 amino acid member of the Bestrophin family of proteins. Members of the Bestrophin family are transmembrane proteins that contain a high percentage of aromatic residues, a conserved RFP (arg-phe-pro) motif and they function as anion channels. Expressed predominantly in skeletal muscle but also found in spinal cord, brain, testis, thymus, retina and bone marrow, Bestrophin-3 forms calcium-sensitive chloride channels. In addition, Bestrophin-3 contains an AI (auto-inhibitory) domain that is capable of regulating the anion channel activity. Due to alternative splicing events, three isoforms exist for Bestrophin-3.

Function:
Forms calcium-sensitive chloride channels. Permeable to bicarbonate.

Subcellular Location:
Cell membrane.

Tissue Specificity:
Present in skeletal muscle and weakly in brain, spinal cord, bone marrow and retina.

Similarity:
Belongs to the bestrophin family.

SWISS:
Q8N1M1

Gene ID:
144453

Database links:

Entrez Gene: 144453 Human

Entrez Gene: 382427 Mouse

Entrez Gene: 314847 Rat

Omim: 607337 Human

SwissProt: Q8N1M1 Human

SwissProt: Q6H1V1 Mouse

Unigene: 280782 Human

Unigene: 339322 Mouse

Unigene: 162940 Rat



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