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Rabbit Anti-KY  antibody (bs-11174R)  
~~~促銷代碼KT202411~~~
訂購熱線:400-901-9800
訂購郵箱:sales@xucheq.com
訂購QQ:  400-901-9800
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說明書: 50ul  100ul  200ul
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包裝/詢價
產(chǎn)品編號 bs-11174R
英文名稱 Rabbit Anti-KY  antibody
中文名稱 脊柱側(cè)后凸畸形肽酶抗體
別    名 KY; KY_HUMAN; Kyphoscoliosis peptidase.  
研究領(lǐng)域 發(fā)育生物學  神經(jīng)生物學  細胞粘附分子  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human,Mouse,Rat,Pig,Dog)
產(chǎn)品應(yīng)用 WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 75kDa
細胞定位 細胞漿 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from mouse Kyphoscoliosis peptidase: 51-150/661 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 KY peptidase (Kyphoscoliosis peptidase) is a 561 amino acid cytoskeleton protease that interacts with several sarcomeric cytoskeletal proteins, including Filamin 2. KY peptidase probably plays a role in the maturation, function and stabilization of the neuromuscular junction. KY-null mouse mutants exhibit distinct irregular subceullular Filamin 2 localization, suggesting that KY peptidase deficiency may be the cause of several types of limb-girdle muscular dystrophies.

Function:
Probable cytoskeleton-associated protease required for normal muscle growth. Involved in function, maturation and stabilization of the neuromuscular junction. May act by cleaving muscle-specific proteins such as FLNC.

Subunit:
Interacts with IGFN1 and FLNC.

Subcellular Location:
Cytoplasm

Tissue Specificity:
Specifically expressed in skeletal and cardiac muscle.

Similarity:
Belongs to the transglutaminase-like superfamily.

SWISS:
Q8NBH2

Gene ID:
339855

Database links:

Entrez Gene: 339855 Human

Entrez Gene: 16716 Mouse

Omim: 605739 Human

SwissProt: Q8NBH2 Human

SwissProt: Q8C8H8 Mouse

Unigene: 146730 Human



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