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Rabbit Anti-P2RX5  antibody (bs-12108R)  
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產(chǎn)品編號 bs-12108R
英文名稱 Rabbit Anti-P2RX5  antibody
中文名稱 三磷酸腺苷受體P2X5抗體
別    名 ATP receptor; ATP receptor subunit; Ionotropic ATP receptor P2X5; LRH 1; LRH1; Lymphoid restricted histocompatibility antigen 1; MGC47755; P2rx5; P2RX5_HUMAN; P2X purinoceptor 5; P2X5; P2X5R; Purinergic receptor; Purinergic receptor P2X ligand gated ion channel 5; Purinergic receptor P2X5.  
研究領(lǐng)域 神經(jīng)生物學(xué)  細胞凋亡  通道蛋白  細胞膜受體  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Mouse (predicted: Human,Rat,Pig,Sheep,Cow,Dog)
產(chǎn)品應(yīng)用 WB=1:500-2000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 47kDa
細胞定位 細胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human P2RX5: 251-350/422 <Extracellular>
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 The P2X receptor family is comprised of ligand-gated ion channels that allow for the increased permeability of calcium into the cell in response to extracellular ATP. The seven P2X receptors, P2X1-P2X7, form either homomeric or heteromeric channels or both. They are characterized by intracellular amino- and carboxy-termini. P2X receptors are expressed in a wide variety of tissues, including neurons, prostate, bladder, pancreas, colon, testis and ovary. The major function of the P2X receptors is to mediate synaptic transmissions between neurons and to other tissues via the binding of extracellular ATP, which acts as a neurotransmitter. The P2X receptors may be involved in the onset of necrosis or apoptosis after prolonged exposure to high concentrations of extracellular ATP.

Function:
Receptor for ATP that acts as a ligand-gated ion channel.

Subunit:
Functional P2XRs are organized as homomeric and heteromeric trimers

Subcellular Location:
Membrane; Multi-pass membrane protein.

Tissue Specificity:
Expressed at high levels in brain and immune system.

Similarity:
Belongs to the P2X receptor family.

SWISS:
Q93086

Gene ID:
5026

Database links:

Entrez Gene: 5026 Human

Entrez Gene: 94045 Mouse

Entrez Gene: 113995 Rat

Omim: 602836 Human

SwissProt: Q93086 Human

SwissProt: P51578 Rat

Unigene: 408615 Human

Unigene: 731607 Human

Unigene: 156893 Mouse

Unigene: 10257 Rat



產(chǎn)品圖片
Sample: Heart (Mouse) Lysate at 40 ug Primary: Anti-P2RX5 (bs-12108R) at 1/300 dilution Secondary: HRP conjugated Goat-Anti-rabbit IgG (bs-0295G-HRP) at 1/5000 dilution Predicted band size: 47 kD Observed band size: 47 kD
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