| 產(chǎn)品編號 | bs-12129R |
| 英文名稱 | Rabbit Anti-ACCN4 antibody |
| 中文名稱 | 腦鈉通道蛋白4抗體 |
| 別 名 | Accn4; ACCN4_HUMAN; Acid sensing (proton gated) ion channel family member 4; Acid sensing ion channel 4; Acid-sensing ion channel 4; Amiloride sensitive cation channel 4; Amiloride sensitive cation channel 4 pituitary; Amiloride sensitive cation channel family member 4 pituitary; Amiloride-sensitive cation channel 4; Amiloride-sensitive cation channel 4; ASIC4; BNAC4; Brain sodium channel 4; pituitary. |
| 研究領(lǐng)域 | 神經(jīng)生物學(xué) 通道蛋白 細(xì)胞膜受體 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human,Mouse,Rat,Pig,Sheep,Cow,Dog,Horse) |
| 產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 70kDa |
| 細(xì)胞定位 | 細(xì)胞膜 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human ACCN4/ASIC4: 451-550/647 <Extracellular> |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
This gene belongs to the superfamily of acid-sensing ion channels, which are proton-gated, amiloride-sensitive sodium channels. These channels have been implicated in synaptic transmission, pain perception as well as mechanoperception. This gene is predominantly expressed in the pituitary gland, and was considered a candidate for paroxysmal dystonic choreoathetosis (PDC), a movement disorder, however, no correlation was found between mutations in this gene and PDC. [provided by RefSeq, Feb 2012].
Function: Probable cation channel with high affinity for sodium. In vitro, has no proton-gated channel activity. Subunit: Homotrimer or heterotrimer with other ASIC proteins. Subcellular Location: .Membrane; Multi-pass membrane protein. Tissue Specificity: Expressed in pituitary gland. Weakly expressed in brain, vestibular system and organ of Corti. Similarity: Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. ACCN4 subfamily. SWISS: Q96FT7 Gene ID: 55515 Database links: Entrez Gene: 55515 Human Entrez Gene: 241118 Mouse Omim: 606715 Human SwissProt: Q96FT7 Human SwissProt: Q7TNS7 Mouse Unigene: 87469 Human Unigene: 110790 Mouse Unigene: 44831 Rat |
