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Rabbit Anti-NAV3  antibody (bs-12151R)  
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產(chǎn)品編號 bs-12151R
英文名稱 Rabbit Anti-NAV3  antibody
中文名稱 神經(jīng)元引導蛋白3抗體
別    名 KIAA0938; NAV 3; NAV3; NAV3_HUMAN; Neuron navigator 3; POMFIL1; Pore membrane and/or filament-interacting-like protein 1; Steerin 3; Steerin-3; STEERIN3; Unc 53 homolog 3; Unc-53 homolog 3; unc53H3.  
Specific References  (1)     |     bs-12151R has been referenced in 1 publications.
[IF=24.633] Yanxin Li. et al. Decoding the temporal and regional specification of microglia in the developing human brain. Cell Stem Cell. 2022 Mar;:  IF ;  Mouse,Human.  
研究領(lǐng)域 細胞生物  神經(jīng)生物學  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Mouse (predicted: Human,Rat,Sheep,Chicken,Horse)
產(chǎn)品應用 WB=1:500-2000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 255kDa
細胞定位 細胞核 細胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human NAV3: 301-400/2385 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 May regulate IL2 production by T-cells. May be involved in neuron regeneration.

Function:
May regulate IL2 production by T-cells. May be involved in neuron regeneration.

Subcellular Location:
Nucleus outer membrane.

Tissue Specificity:
Highly expressed in brain. Expressed at low levels in heart and placenta. Present in activated T-cells but not in resting T-cells (at protein level). Down-regulated in primary neuroblastoma.

DISEASE:
Note=A chromosomal aberration disrupting NAV3 has been found in patients with Sezary syndrome. Translocation t(12;18)(q21;q21.2).

Similarity:
Sequence similarities; Belongs to the Nav/unc-53 family.
Contains 1 CH (calponin-homology) domain.

SWISS:
Q8IVL0

Gene ID:
89795

Database links:

Entrez Gene: 89795 Human

Entrez Gene: 260315 Mouse

Entrez Gene: 314814 Rat

Omim: 611629 Human

SwissProt: Q8IVL0 Human

SwissProt: Q80TN7 Mouse

Unigene: 655301 Human

Unigene: 225050 Mouse

Unigene: 394160 Mouse

Unigene: 461280 Mouse



產(chǎn)品圖片
Sample: Cerebrum (Mouse) Lysate at 40 ug Primary: Anti- NAV3 (bs-12151R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 255 kD Observed band size: 255 kD
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