產(chǎn)品編號 | bs-12242R |
英文名稱 | Rabbit Anti-ZFP100 / ZNF473 antibody |
中文名稱 | 鋅指蛋白100/鋅指蛋白473抗體 |
別 名 | HZFP100; Zfp 100; Zfp-100; Zinc finger protein 100 homolog; Zinc finger protein 473; zinc finger protein ZFP100; ZN473_HUMAN. |
研究領(lǐng)域 | 轉(zhuǎn)錄調(diào)節(jié)因子 鋅指蛋白 表觀遺傳學(xué) |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | Mouse (predicted: Human,Rat,Rabbit,Cow,Dog,Horse) |
產(chǎn)品應(yīng)用 | WB=1:500-2000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理論分子量 | 100kDa |
細(xì)胞定位 | 細(xì)胞核 |
性 狀 | Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human ZFP100/ZNF473: 701-830/871 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
產(chǎn)品介紹 |
Involved in histone 3'-end pre-mRNA processing by associating with U7 snRNP and interacting with SLBP/pre-mRNA complex. Increases histone 3'-end pre-mRNA processing but has no effect on U7 snRNP levels, when overexpressed. Required for cell cycle progression from G1 to S phases. Function: Involved in histone 3'-end pre-mRNA processing by associating with U7 snRNP and interacting with SLBP/pre-mRNA complex. Increases histone 3'-end pre-mRNA processing but has no effect on U7 snRNP levels, when overexpressed. Required for cell cycle progression from G1 to S phases. Subunit: Interacts with the SLBP/pre-mRNA complex but not with SLBP alone. Interacts with LSM11 in a U7 snRNP-dependent manner. Subcellular Location: Nucleus. Stable component of Cajal bodies (CBs). Colocalizes with SMN, coilin and U7 snRNA. Similarity: Belongs to the krueppel C2H2-type zinc-finger protein family. Contains 20 C2H2-type zinc fingers. Contains 1 KRAB domain. SWISS: Q8WTR7 Gene ID: 25888 Database links: Entrez Gene: 25888 Human SwissProt: Q8WTR7 Human Unigene: 440553 Human |
產(chǎn)品圖片 | |