吃奶呻吟打开双腿做受动态图 -亚洲色偷偷色噜噜狠狠99网-日韩精品极品视频在线观看免费-来一水AV@lysav

掃碼關(guān)注公眾號(hào)           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  人才招聘  關(guān)于我們  聯(lián)系我們
国内老熟妇对白XXXXHD,久久9精品区-无套内射无码,女人与公驹交酡全过程
首頁(yè) > 產(chǎn)品中心 > 一抗 > 產(chǎn)品信息
Rabbit Anti-MEGF10  antibody (bs-12372R)  
~~~促銷代碼KT202411~~~
訂購(gòu)熱線:400-901-9800
訂購(gòu)郵箱:sales@xucheq.com
訂購(gòu)QQ:  400-901-9800
技術(shù)支持:techsupport@xucheq.com
說(shuō)明書: 50ul  100ul  200ul
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-12372R
英文名稱 Rabbit Anti-MEGF10  antibody
中文名稱 表皮生長(zhǎng)因子樣蛋白Megf10抗體
別    名 MEG10_HUMAN; MEGF protein; megf10; Multiple EGF-like domains protein 10; multiple EGF-like-domains 10; Multiple epidermal growth factor-like domains 10; Multiple epidermal growth factor-like domains protein 10.  
研究領(lǐng)域 細(xì)胞生物  發(fā)育生物學(xué)  干細(xì)胞  細(xì)胞凋亡  生長(zhǎng)因子和激素  新陳代謝  
抗體來(lái)源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human,Mouse,Rat,Pig,Sheep,Cow,Chicken,Dog,Horse)
產(chǎn)品應(yīng)用 ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 119kDa
細(xì)胞定位 細(xì)胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human MEGF10: 55-150/1140 <Extracellular>
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項(xiàng) This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 MEGF10 is a 1,140 amino acid protein encoded by the human gene MEGF10. MEGF10 belongs to the MEGF family and contains fifteen EGF-like domains and one EMI domain. The engulfment of dying cells is a specialized form of phagocytosis that is highly conserved across evolution and is mediated by the concerted action of several molecules. MEGF10 is an engulfment receptor protein that localizes to the plasma membrane in a punctuated pattern. The MEGF10 protein shares structural similarities with nematode engulfment receptor cell death abnormal-1 (CED-1). MEGF10 function is modulated by the ATP binding cassette transporter ABCA1, which is an ortholog to CED-7. It is expressed at the cell surface in clusters around cell corpses during engulfment, and during the engulfment of apoptotic thymocytes is recruited to the bottom of the forming phagocytic cup.

Function:
Involved in phagocytosis by macrophages of apoptotic cells. Cooperates with ABCA1 during engulfment. Destabilizes the oligomeric assemblies of the ABCA1 transporter. Plays a role in cell adhesion. Inhibits cell motility and cell proliferation in vitro. Promotes formation of large intracellular vacuoles.

Subunit:
Homopolymer (Probable). Interacts with GULP1 and ABCA1. Interacts with AP2M1. Does not interact with MEGF11.

Subcellular Location:
Cell membrane.

Post-translational modifications:
Phosphorylated on tyrosine residues.
Ubiquinated; mono- and polyubiquitinated forms are detected.

DISEASE:
Defects in MEGF10 are the cause of myopathy, early-onset, areflexia, respiratory distress, and dysphagia (EMARDD) [MIM:614399]. An autosomal recessive congenital myopathy characterized by onset at birth, or early in infancy, of respiratory distress caused by diaphragmatic weakness. Additional features are dysphagia resulting in poor feeding, failure to thrive, poor head control, facial weakness, cleft palate, contractures and scoliosis. Affected individuals become ventilator-dependent, and most require feeding by gastrostomy. The disorder results in severe muscle weakness and most patients never achieve walking. Death from respiratory failure in childhood occurs in about half of patients. Muscle biopsy shows myopathic changes, replacement of myofibers with fatty tissue, small and incompletely fused muscle fibers, and variation in fiber size. Short regions of sarcomeric disorganization with few or no mitochondria (minicores) have been observed in some cases.

Similarity:
Belongs to the MEGF family.
Contains 15 EGF-like domains.
Contains 1 EMI domain.

SWISS:
Q96KG7

Gene ID:
84466

Database links:

Entrez Gene: 84466 Human

SwissProt: Q96KG7 Human



版權(quán)所有 2004-2026 www.xucheq.com 北京博奧森生物技術(shù)有限公司
通過(guò)國(guó)際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號(hào): 00124Q34771R2M/1100
通過(guò)國(guó)際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號(hào): CQC24QY10047R0M/1100
京ICP備05066980號(hào)-1         京公網(wǎng)安備110107000727號(hào)
人妻含泪让粗大挺进| 熟女性饥渴一区二区三区| 久久久久夜夜夜精品国产| 日韩精品一区二区亚洲AV观看| 熟妇人妻中文字幕| 国产日产欧产美| 色欲AV伊人久久大香线蕉影院| 国产精品一区二区在线观看| 狠狠色综合7777久夜色撩人,| 欧美高清性色生活片免费观看| 两女互摸自慰喷水爽哭直播了| 国内精品一区二区三区| 无码人妻AV免费一区二区三区| 成人午夜亚洲精品无码网站 | 国模吧| 久激情内射婷内射蜜桃| 亚洲乱码日产精品BD在线观看 | 日韩欧美亚洲国产精品字幕久久久| 久久久久亚洲AV片无码| 999国产精品999久久久久久| 娇妻被领导粗又大又硬| 欧美黑人又粗又大久久久| 少妇极品熟妇人妻无码| 亚洲日韩精品a∨片无码| 男人J桶进女人P无遮挡全过程 | 重口老太大和小伙乱| 偷玩同学漂亮麻麻张嫣| 成人小说亚洲一区二区三区| 成人区人妻精品一区二区不卡视频| 国产免费一区二区三区在线观看 | 曰本无码人妻丰满熟妇啪啪| 国产精品美女久久久久AV爽 | 亚洲精品乱码久久久久久不卡| 18禁男女爽爽爽午夜网站免费 | 天天操,天天干,天天日 | 老头猛挺进小雯的体内视频| 又粗又黄又猛又爽大片免费| 亚洲大尺度无码专区尤物| 俄罗斯大荫蒂女人毛茸茸| 精品成在人线AV无码免费看| 少妇AV射精精品蜜桃专区|