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Rabbit Anti-Alpha SNAP  antibody (bs-12465R)  
~~~促銷代碼KT202411~~~
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50ul/1180.00元
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200ul/2800.00元
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產(chǎn)品編號 bs-12465R
英文名稱 Rabbit Anti-Alpha SNAP  antibody
中文名稱 可溶性附著蛋白α-SNAP抗體
別    名 Alpha soluble NSF attachment protein; Alpha-soluble NSF attachment protein; N ethylmaleimide sensitive factor attachment protein alpha; N-ethylmaleimide-sensitive factor attachment protein alpha; NAPA; SNAA_HUMAN; SNAP alpha; SNAP alpha; SNAP-alpha; SNAPA.  
研究領(lǐng)域 細胞生物  信號轉(zhuǎn)導(dǎo)  轉(zhuǎn)運蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human,Mouse,Rat,Pig,Cow,Dog)
產(chǎn)品應(yīng)用 WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 33kDa
細胞定位 細胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Alpha SNAP: 201-295/295 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 Syntaxins were originally thought to be docking proteins, but have more recently been categorized as anchoring proteins that anchor themselves to the cytoplasmic surfaces of cellular membranes. Syntaxins have been shown to bind to various proteins involved in exocytosis, including VAMPs (vesicle-associated membrane proteins), NSF (N-ethylmaleimide-sensitive factor), SNAP 25 (synaptosomal-associated protein of 25kDa), SNAPs (soluble NSF attachment proteins) and synaptotagmin. VAMPs (also designated synaptobrevins), including VAMP-1 and VAMP-2, and synaptotagmin, a protein that may function as an inhibitor of exocytosis, are vesicular proteins.

Function:
Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus.

Subunit:
Interacts with PRKCABP, and disrupts the interaction between GRIA2 and PRKCABP, leading to the internalization of GRIA2. Found in a complex with VAMP8 (By similarity). Component of a SNARE-like complex that contains at least ZW10, USE1L, RINT1, STX18 and NAPA/SNAP-alpha. Interacts with VTI1A. Interacts with STX12 (By similarity).

Subcellular Location:
Membrane; Peripheral membrane protein.

Similarity:
Belongs to the SNAP family.

SWISS:
P54920

Gene ID:
8775

Database links:

Entrez Gene: 518407 Cow

Entrez Gene: 8775 Human

Entrez Gene: 108124 Mouse

Entrez Gene: 140673 Rat

Omim: 603215 Human

SwissProt: P81125 Cow

SwissProt: P54920 Human

SwissProt: Q9DB05 Mouse

SwissProt: P54921 Rat

Unigene: 126938 Human

Unigene: 727492 Human

Unigene: 104540 Mouse

Unigene: 431371 Mouse

Unigene: 31745 Rat



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