| 產(chǎn)品編號 | bs-10232R |
| 英文名稱 | Rabbit Anti-CD93 antibody |
| 中文名稱 | CD93抗體 |
| 別 名 | C1qrp; Complement component C1q receptor; C1q/MBL/SPA receptor; C1qR(p); C1qr1; C1qRp; CD93 antigen; CD93 molecule; CDw93; Complement component 1 q subcomponent receptor 1; Complement component C1q receptor; dJ737E23.1; ECSM3; Ly68; Matrix remodeling associated protein 4; MXRA4. |
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Specific References (2) | bs-10232R has been referenced in 2 publications.
[IF=14.957] Weiwei Xiao. et al. Recombinant DTβ4-inspired porous 3D vascular graft enhanced antithrombogenicity and recruited circulating CD93+/CD34+ cells for endothelialization. SCI ADV. 2022 Jul;8(28) IF ; Rat.
[IF=5.31] Chen Su. et al. CD93 in macrophages: A novel target for atherosclerotic plaque imaging?. 2022 Feb 15 IF ; Rat.
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| 研究領(lǐng)域 | 免疫學(xué) 細(xì)胞粘附分子 細(xì)胞表面分子 糖蛋白 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | Human (predicted: Mouse,Rat,Dog) |
| 產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 70kDa |
| 細(xì)胞定位 | 細(xì)胞膜 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human CD93: 56-160/652 <Extracellular> |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
The protein encoded by this gene is a cell-surface glycoprotein and type I membrane protein that was originally identified as a myeloid cell-specific marker. The encoded protein was once thought to be a receptor for C1q, but now is thought to instead be involved in intercellular adhesion and in the clearance of apoptotic cells. The intracellular cytoplasmic tail of this protein has been found to interact with moesin, a protein known to play a role in linking transmembrane proteins to the cytoskeleton and in the remodelling of the cytoskeleton. [provided by RefSeq, Jul 2008]. Function: Receptor (or element of a larger receptor complex) for C1q, mannose-binding lectin (MBL2) and pulmonary surfactant protein A (SPA). May mediate the enhancement of phagocytosis in monocytes and macrophages upon interaction with soluble defense collagens. May play a role in intercellular adhesion. Subunit: Interacts with HCV core protein. Interacts with C1QBP; the association may represent a cell surface C1q receptor. Subcellular Location: Membrane; Single-pass type I membrane protein. Tissue Specificity: Highly expressed in endothelial cells, platelets, cells of myeloid origin, such as monocytes and neutrophils. Not expressed in cells of lymphoid origin. Post-translational modifications: N- and O-glycosylated. Similarity: Contains 1 C-type lectin domain. Contains 5 EGF-like domains. SWISS: Q9NPY3 Gene ID: 22918 Database links: Entrez Gene: 22918 Human Entrez Gene: 17064 Mouse Omim: 120577 Human SwissProt: Q9NPY3 Human SwissProt: O89103 Mouse Unigene: 97199 Human Unigene: 681 Mouse Unigene: 162695 Rat |
| 產(chǎn)品圖片 |
Tissue/cell: human kidney tissue; 4% Paraformaldehyde-fixed and paraffin-embedded;
Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,C-0005) at 37℃ for 20 min;
Incubation: Anti-CD93 Polyclonal Antibody, Unconjugated(bs-10232R) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody(SP-0023) and DAB(C-0010) staining
Tissue/cell: human lung carcinoma; 4% Paraformaldehyde-fixed and paraffin-embedded;
Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,C-0005) at 37℃ for 20 min;
Incubation: Anti-CD93 Polyclonal Antibody, Unconjugated(bs-10232R) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody(SP-0023) and DAB(C-0010) staining
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