| 產(chǎn)品編號 | bs-13062R |
| 英文名稱 | Rabbit Anti-EGFL6 antibody |
| 中文名稱 | 表皮生長因子樣蛋白6抗體 |
| 別 名 | EGF like domain multiple 6; EGF repeat containing protein 6; EGF-like protein 6; EGF-like-domain multiple 6; egfl6; EGFL6_HUMAN; epidermal growth factor like protein 6; Epidermal growth factor-like protein 6; MAEG; MAM and EGF domain containing; MAM and EGF domains containing gene protein; MAM and EGF domains-containing gene protein; W80. |
| 研究領(lǐng)域 | 腫瘤 細(xì)胞生物 神經(jīng)生物學(xué) 生長因子和激素 細(xì)胞粘附分子 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human,Mouse,Rat,Sheep,Cow,Dog,Horse) |
| 產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 59kDa |
| 細(xì)胞定位 | 細(xì)胞膜 細(xì)胞外基質(zhì) 分泌型蛋白 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human EGFL6: 231-330/553 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
This gene encodes a member of the epidermal growth factor(EGF) repeat superfamily. Members of this superfamily arecharacterized by the presence of EGF-like repeats and are ofteninvolved in the regulation of cell cycle, proliferation, anddevelopmental processes. The gene product contains a signalpeptide, suggesting that it is secreted; an EGF repeat regionconsisting of 4 complete EGF-like repeats and 1 partial EGF-likerepeat, 3 of which have a calcium-binding consensus sequence; anarg-gly-asp integrin association motif; and a MAM domain, which isbelieved to have an adhesive function. This gene is expressed earlyduring development, and its expression has been detected in lungand meningioma tumors. [provided by RefSeq, Jul 2008]. Function: May bind integrin alpha-8/beta-1 and play a role in hair follicle morphogenesis. Promotes matrix assembly. Subcellular Location: Secreted, extracellular space, extracellularmatrix, basement membrane (By similarity). Similarity: Belongs to the nephronectin family. Contains 5 EGF-like domains. Contains 1 MAM domain. SWISS: Q8IUX8 Gene ID: 25975 Database links: Entrez Gene: 25975 Human Entrez Gene: 54156 Mouse Omim: 300239 Human SwissProt: Q8IUX8 Human SwissProt: Q9JJZ5 Mouse |
