吃奶呻吟打开双腿做受动态图 -亚洲色偷偷色噜噜狠狠99网-日韩精品极品视频在线观看免费-来一水AV@lysav

掃碼關(guān)注公眾號           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  人才招聘  關(guān)于我們  聯(lián)系我們
国产精品扒开腿做爽爽爽A片小说,人人妻人人添人人爽欧美一区,自拍日韩亚洲一区在线
首頁 > 產(chǎn)品中心 > 一抗 > 產(chǎn)品信息
Rabbit Anti-EpCAM  antibody (bs-4889R)  
~~~促銷代碼KT202411~~~
訂購熱線:400-901-9800
訂購郵箱:sales@xucheq.com
訂購QQ:  400-901-9800
技術(shù)支持:techsupport@xucheq.com
說明書: 50ul  100ul  200ul
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包裝/詢價

產(chǎn)品編號 bs-4889R
英文名稱 Rabbit Anti-EpCAM  antibody
中文名稱 上皮細(xì)胞粘附分子(CD326)抗體
別    名 Adenocarcinoma associated antigen; CD326; CD326 antigen; Cell surface glycoprotein Trop 1; CO17 1A; EGP; EGP40; Ep CAM; Epithelial cell surface antigen; Epithelial cellular adhesion molecule; Epithelial glycoprotein; GA733 2; hEGP 2; KS 1/4 antigen; KSA; Lymphocyte antigen 74; M1S2; M4S1; Major gastrointestinal tumor associated protein GA733 2; MIC18; MK 1; TACD1; TACSTD1; TROP1; Tumor associated calcium signal transducer 1.  
Specific References  (1)     |     bs-4889R has been referenced in 1 publications.
[IF=6.389] Ravindra D. Wavhale. et al. Self-Propelled Catalytically Powered Dual-Engine Magnetic Nanobots for Rapid and Highly Efficient Capture of Circulating Fetal Trophoblasts. ADV MATER INTERFACES. 2022 Jul 06  IA ;  Human.  
研究領(lǐng)域 腫瘤  細(xì)胞生物  免疫學(xué)  細(xì)胞粘附分子  細(xì)胞表面分子  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human,Mouse (predicted: Rat)
產(chǎn)品應(yīng)用 WB=1:500-2000,Flow-Cyt=3ug/Test
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 35kDa
細(xì)胞定位 細(xì)胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human EpCAM: 101-200/314 <Extracellular>
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 This gene encodes a carcinoma-associated antigen and is a member of a family that includes at least two type I membrane proteins. This antigen is expressed on most normal epithelial cells and gastrointestinal carcinomas and functions as a homotypic calcium-independent cell adhesion molecule. The antigen is being used as a target for immunotherapy treatment of human carcinomas. Mutations in this gene result in congenital tufting enteropathy. [provided by RefSeq, Dec 2008]

Function:
May act as a physical homophilic interaction molecule between intestinal epithelial cells (IECs) and intraepithelial lymphocytes (IELs) at the mucosal epithelium for providing immunological barrier as a first line of defense against mucosal infection. Plays a role in embryonic stem cells proliferation and differentiation. Up-regulates the expression of FABP5, MYC and cyclins A and E.

Subunit:
Monomer. Interacts with phosphorylated CLDN7.

Subcellular Location:
Lateral cell membrane; Single-pass type I membrane protein. Cell junction, tight junction. Note=Co-localizes with CLDN7 at the lateral cell membrane and tight junction.

Tissue Specificity:
Highly and selectively expressed by undifferentiated rather than differentiated embryonic stem cells (ESC). Levels rapidly diminish as soon as ESC's differentiate (at protein levels). Expressed in almost all epithelial cell membranes but not on mesodermal or neural cell membranes. Found on the surface of adenocarcinoma.

Post-translational modifications:
Hyperglycosylated in carcinoma tissue as compared with autologous normal epithelia. Glycosylation at Asn-198 is crucial for protein stability.

DISEASE:
Defects in EPCAM are the cause of diarrhea type 5 (DIAR5) [MIM:613217]. It is an intractable diarrhea of infancy characterized by villous atrophy and absence of inflammation, with intestinal epithelial cell dysplasia manifesting as focal epithelial tufts in the duodenum and jejunum. Defects in EPCAM are a cause of hereditary non-polyposis colorectal cancer type 8 (HNPCC8) [MIM:613244]. HNPCC is a disease associated with marked increase in cancer susceptibility. It is characterized by a familial predisposition to early-onset colorectal carcinoma (CRC) and extra-colonic tumors of the gastrointestinal, urological and female reproductive tracts. HNPCC is reported to be the most common form of inherited colorectal cancer in the Western world. Clinically, HNPCC is often divided into two subgroups. Type I is characterized by hereditary predisposition to colorectal cancer, a young age of onset, and carcinoma observed in the proximal colon. Type II is characterized by increased risk for cancers in certain tissues such as the uterus, ovary, breast, stomach, small intestine, skin, and larynx in addition to the colon. Diagnosis of classical HNPCC is based on the Amsterdam criteria: 3 or more relatives affected by colorectal cancer, one a first degree relative of the other two; 2 or more generation affected; 1 or more colorectal cancers presenting before 50 years of age; exclusion of hereditary polyposis syndromes. The term 'suspected HNPCC' or 'incomplete HNPCC' can be used to describe families who do not or only partially fulfill the Amsterdam criteria, but in whom a genetic basis for colon cancer is strongly suspected. Note=HNPCC8 results from heterozygous deletion of 3-prime exons of EPCAM and intergenic regions directly upstream of MSH2, resulting in transcriptional read-through and epigenetic silencing of MSH2 in tissues expressing EPCAM.

Similarity:
Belongs to the EPCAM family.
Contains 1 thyroglobulin type-1 domain.

SWISS:
P16422

Gene ID:
4072

Database links:

Entrez Gene: 4072 Human

Entrez Gene: 17075 Mouse

Entrez Gene: 171577 Rat

Omim: 185535 Human

SwissProt: P16422 Human

SwissProt: Q99JW5 Mouse

SwissProt: O55159 Rat

Unigene: 542050 Human

Unigene: 4259 Mouse

Unigene: 106481 Rat



產(chǎn)品圖片
Sample: Lane 1: Large intestine (Mouse) Lysate at 40 ug Lane 2: Small intestine (Mouse) Lysate at 40 ug Primary: Anti-EpCAM (bs-4889R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 35 kD Observed band size: 38 kD
Blank control: A431. Primary Antibody (green line): Rabbit Anti-TEpCAM antibody (bs-4889R) Dilution: 3μg /10^6 cells; Isotype Control Antibody (orange line): Rabbit IgG . Secondary Antibody: Goat anti-rabbit IgG-AF647 Dilution: 3μg /test. Protocol The cells were incubated in 5%BSA to block non-specific protein-protein interactions for 30 min at at room temperature .Cells stained with Primary Antibody for 30 min at room temperature. The secondary antibody used for 40 min at room temperature. Acquisition of 20,000 events was performed.
版權(quán)所有 2004-2026 www.xucheq.com 北京博奧森生物技術(shù)有限公司
通過國際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網(wǎng)安備110107000727號
午夜亚洲AV永久无码精品| 国产欧美一区二区三区在线看| 少妇扒开双腿自慰出白浆| 人妻妺妺窝人体色WWW聚色窝 | SPY3WC撒SPY3WC撒尿| 亚洲中文字幕无码AV| 开心激情站| 一本色道久久综合亚洲精品| 欧美性猛交XXXX免费看| 97人妻人人揉人人躁人人| 一个人看的视频免费高清在线观看| 高清欧美性猛交XXXX黑人猛交| 亚洲AV在线观看| 99精产国品一二三产区区别电影| 亚洲AV人人澡人人爽人人夜夜| 性欧美xxxxx乱极品少妇| 日韩激情| 又湿又紧又大又爽A视频| 国产伦精品一区二区三区| A级毛片无码免费真人久久| 精品亚洲麻豆1区2区3区| 精品乱人伦一区二区三区| 18禁网站| 99久久国产露脸国语对白| 亚洲国产成人精品无码区二本| 激情无码人妻又粗又大| 亚洲乱码国产乱码精品精| 图片区小说区激情区偷拍区| 亚洲日韩欧美一区久久久久我 | 无码专区AAAAAA免费视频 | 99久久精品国产一区二区三区 | 最近中文字幕高清字幕MV| 久久无码人妻一区二区三区 | 14表妺好紧没带套18分钟| 日韩视频在线观看| 狠狠色婷婷久久一区二区三区| 99久久久无码国产精品9| 亚洲精品久久无码AV片俺去也| 亚洲色偷偷综合亚洲AV伊人 | 一性一交一口添一摸视频| 国产精品特级毛片一区二区三区|