| 產(chǎn)品編號(hào) | bs-14032R |
| 英文名稱 | Rabbit Anti-CPNE9 antibody |
| 中文名稱 | 鈣依賴膜結(jié)合蛋白Copine蛋白9抗體 |
| 別 名 | Copine 9; Copine family member IX; Copine IX; CPNE9_HUMAN; Copine like protein. |
| 研究領(lǐng)域 | 細(xì)胞生物 信號(hào)轉(zhuǎn)導(dǎo) 轉(zhuǎn)運(yùn)蛋白 細(xì)胞膜蛋白 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human,Mouse,Rat,Rabbit,Cow,Dog,Horse) |
| 產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 62kDa |
| 細(xì)胞定位 | 細(xì)胞膜 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human CPNE9: 21-120/553 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
Copine 9 is a 503 amino acid member of the copine family of evolutionarily conserved, soluble, calcium-dependent, membrane-binding proteins. Members of the copine family are involved in signal transduction and membrane trafficking. Arabidopsis thaliana mutants lacking copine proteins exhibit reduced cell number and smaller cell size, effects which may be due to a defect in vesicle fusion or transport. Copine 9 contains two N-terminal C2 domains and one C-terminal VWFA (von Willebrand factor A) domain, which is also referred to as the A domain or the core domain. As is characteristic of the copine family, copine 9 functions in membrane trafficking and is capable of binding phospholipids in a calcium-dependent manner. Function: The exact functions of CPNE9 remain unknown but it may function in membrane trafficking. CPNE9 exhibits calcium-dependent phospholipid binding properties. Similarity: Belongs to the copine family. Contains 2 C2 domains. Contains 1 VWFA domain. SWISS: Q8IYJ1 Gene ID: 151835 Database links: Entrez Gene: 151835 Human Entrez Gene: 211232 Mouse SwissProt: Q8IYJ1 Human SwissProt: Q1RLL3 Mouse Unigene: 121335 Human |
