產(chǎn)品編號 | bs-14212R |
英文名稱 | Rabbit Anti-DDI1 antibody |
中文名稱 | DNA損傷誘導(dǎo)蛋白1抗體 |
別 名 | ddi1; DDI1 DNA damage inducible 1 homolog 1; DDI1_HUMAN; DNA-damage inducible 1, homolog 1; DNA-damage inducible protein 1; FLJ36017; OTTHUMP00000231644; Protein DDI1 homolog 1. |
研究領(lǐng)域 | 細(xì)胞生物 細(xì)胞凋亡 細(xì)胞周期蛋白 泛素 |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | (predicted: Human,Mouse,Rat,Rabbit,Pig,Dog) |
產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理論分子量 | 44kDa |
細(xì)胞定位 | 細(xì)胞漿 |
性 狀 | Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human DDI1: 101-200/396 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
產(chǎn)品介紹 |
DDI1 is a 396 amino acid protein that contains one ubiquitin-like domain. The gene encoding DDI1 maps to human chromosome 11, which makes up around 4% of human genomic DNA and is considered a gene and disease association dense chromosome. The chromosome 11 encoded Atm gene is important for regulation of cell cycle arrest and apoptosis following double strand DNA breaks. Atm mutation leads to the disorder known as ataxia-telangiectasia. The blood disorders Sickle cell anemia and ∫ thalassemia are caused by HBB gene mutations. Wilms' tumors, WAGR syndrome and Denys-Drash syndrome are associated with mutations of the WT1 gene. Similarity: Belongs to the DDI1 family. Contains 1 ubiquitin-like domain. SWISS: Q8WTU0 Gene ID: 414301 Database links: Entrez Gene: 414301 Human Entrez Gene: 71829 Mouse SwissProt: Human SwissProt: Q8WTU0 Human SwissProt: Q9DAF3 Mouse Unigene: 591941 Human Unigene: 141452 Mouse Unigene: 92290 Rat |