產(chǎn)品編號(hào) | bs-16086R |
英文名稱 | Rabbit Anti-FIBP antibody |
中文名稱 | aFGF胞內(nèi)結(jié)合蛋白抗體 |
別 名 | Acidic fibroblast growth factor intracellular-binding protein; aFGF intracellular-binding protein; FGF-1 intracellular-binding protein; FGFIBP; FIBP; FIBP-1; FIBP_HUMAN; FIBP1; fibroblast growth factor (acidic) intracellular binding protein; OTTHUMP00000234231; OTTHUMP00000234232; OTTHUMP00000234233. |
研究領(lǐng)域 | 細(xì)胞生物 信號(hào)轉(zhuǎn)導(dǎo) 生長因子和激素 |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | (predicted: Human,Mouse,Rat,Rabbit,Pig,Cow,Dog,Horse) |
產(chǎn)品應(yīng)用 | ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理論分子量 | 42kDa |
細(xì)胞定位 | 細(xì)胞核 |
性 狀 | Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human FIBP: 51-150/364 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
產(chǎn)品介紹 |
Acidic fibroblast growth factor is mitogenic for a variety of different cell types and acts by stimulating mitogenesis or inducing morphological changes and differentiation. The FIBP protein is an intracellular protein that binds selectively to acidic fibroblast growth factor (aFGF). It is postulated that FIBP may be involved in the mitogenic action of aFGF. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] Function: May be involved in mitogenic function of FGF1. Subcellular Location: Nucleus. Endomembrane system. Also associated with cytoplasmic membranes, particularly of mitochondria. Tissue Specificity: Highly expressed in heart, skeletal muscle and pancreas. Expressed at lower levels in brain. Also found in placenta, liver and kidney. SWISS: O43427 Gene ID: 9158 Database links: Entrez Gene: 9158 Human Entrez Gene: 58249 Mouse Omim: 608296 Human SwissProt: O43427 Human SwissProt: Q9JI19 Mouse Unigene: 7768 Human Unigene: 329656 Mouse |