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Rabbit Anti-KCNH6  antibody (bs-16887R)  
~~~促銷代碼KT202411~~~
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產(chǎn)品編號 bs-16887R
英文名稱 Rabbit Anti-KCNH6  antibody
中文名稱 KCNH6蛋白抗體
別    名 eag related protein 2; ERG 2; ERG2; ether a go go related gene potassium channel 2; HERG2; Kv11.2; potassium voltage gated channel subfamily H (eag-related), member 6; Voltage-gated potassium channel subunit Kv11.2.  
研究領域 細胞生物  信號轉導  通道蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Rat (predicted: Human)
產(chǎn)品應用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 110kDa
細胞定位 細胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human KCNH6: 401-500/994 <Extracellular>
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 Pore-forming (alpha) subunit of voltage-gated potassium channel. Elicits a slowly activating, rectifying current (By similarity). Channel properties may be modulated by cAMP and subunit assembly.

Subunit:
The potassium channel is probably composed of a homo- or heterotetrameric complex of pore-forming alpha subunits that can associate with modulating beta subunits. Heteromultimers with KCNH2/ERG1 and KCNH7/ERG3 (By similarity).

Subcellular Location:
Membrane; Multi-pass membrane protein.

Tissue Specificity:
Expressed in prolactin-secreting adenomas.

Similarity:
Belongs to the potassium channel family. H (Eag) (TC 1.A.1.20) subfamily.
Kv11.2/KCNH6 sub-subfamily.
Contains 1 cyclic nucleotide-binding domain.
Contains 1 PAC (PAS-associated C-terminal) domain.
Contains 1 PAS (PER-ARNT-SIM) domain.


SWISS:
Q9H252

Gene ID:
81033

Database links:

Entrez Gene: 81033 Human

Entrez Gene: 192775 Mouse

Entrez Gene: 116745 Rat

Omim: 608168 Human

SwissProt: Q9H252 Human

SwissProt: O54853 Rat

Unigene: 591177 Human

Unigene: 343850 Mouse



產(chǎn)品圖片
Paraformaldehyde-fixed, paraffin embedded (rat stomach); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (KCNH6) Polyclonal Antibody, Unconjugated (bs-16887R) at 1:400 overnight at 4°C, followed by a conjugated secondary (sp-0023) for 20 minutes and DAB staining.
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