產(chǎn)品編號(hào) | bs-16918R |
英文名稱 | Rabbit Anti-KCNS3 antibody |
中文名稱 | 電壓門控鉀通道亞基KV9.3抗體 |
別 名 | Delayed rectifier K(+) channel alpha subunit 3; Delayed rectifier K+ channel alpha subunit 3; Delayed-rectifier K(+) channel alpha subunit 3; KCNS 3; Kcns3; KCNS3_HUMAN; KV 9.3; KV9.3; MGC9481; Potassium voltage gated channel delayed rectifier protein S3; Potassium voltage gated channel delayed rectifier subfamily S member 3; Potassium voltage gated channel subfamily S member 3; Potassium voltage-gated channel subfamily S member 3; Shab related delayed rectifier K+ channel alpha subunit 3; Voltage gated potassium channel subunit Kv9.3; Voltage-gated potassium channel subunit Kv9.3. |
研究領(lǐng)域 | 細(xì)胞生物 神經(jīng)生物學(xué) 通道蛋白 |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | Mouse (predicted: Human,Rat,Rabbit,Pig,Sheep,Dog,Horse) |
產(chǎn)品應(yīng)用 | WB=1:500-2000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理論分子量 | 56kDa |
細(xì)胞定位 | 細(xì)胞膜 |
性 狀 | Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human KCNS3: 401-491/491 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
產(chǎn)品介紹 |
Voltage-gated potassium channels form the largest and most diversified class of ion channels and are present in both excitable and nonexcitable cells. Their main functions are associated with the regulation of the resting membrane potential and the control of the shape and frequency of action potentials. The alpha subunits are of 2 types: those that are functional by themselves and those that are electrically silent but capable of modulating the activity of specific functional alpha subunits. The protein encoded by this gene is not functional by itself but can form heteromultimers with member 1 and with member 2 (and possibly other members) of the Shab-related subfamily of potassium voltage-gated channel proteins. This gene belongs to the S subfamily of the potassium channel family. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Sep 2013] Function: Potassium channel subunit. Modulates channel activity and reduces the ion flow. Subunit: Heteromultimer with KCNB1 and with KCNB2. Does not form homomultimers. Might also bind to other channel proteins (By similarity). Subcellular Location: Cell membrane. May not reach the plasma membrane but remain in an intracellular compartment in the absence of KCNB1. Tissue Specificity: Detected in most tissues, but not in peripheral blood lymphocytes. The highest levels of expression are in lung. Similarity: Belongs to the potassium channel family. S (TC 1.A.1.2) subfamily. Kv9.3/KCNS3 sub-subfamily. SWISS: Q9BQ31 Gene ID: 3790 Database links: Entrez Gene: 3790 Human Entrez Gene: 238076 Mouse Omim: 603888 Human SwissProt: Q9BQ31 Human SwissProt: Q8BQZ8 Mouse Unigene: 414489 Human Unigene: 113278 Mouse Unigene: 10878 Rat |
產(chǎn)品圖片 | |