產(chǎn)品編號 | bs-16994R |
英文名稱 | Rabbit Anti-KIAA1191 antibody |
中文名稱 | KIAA1191蛋白抗體 |
別 名 | IR2155535; OTTHUMP00000185569; OTTHUMP00000195036; TMEM2L; P33MX_HUMAN; Transmembrane protein 2 like; Putative monooxygenase p33MONOX; Brain-derived rescue factor p60MONOX; Flavin monooxygenase motif-containing protein of 33 kDa. |
研究領(lǐng)域 | 腫瘤 細(xì)胞生物 免疫學(xué) 神經(jīng)生物學(xué) 腫瘤細(xì)胞生物標(biāo)志物 |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | (predicted: Human,Mouse,Rat,Rabbit,Cow,Dog,Horse) |
產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理論分子量 | 33kDa |
細(xì)胞定位 | 細(xì)胞膜 |
性 狀 | Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human KIAA1191: 51-150/305 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
產(chǎn)品介紹 |
KIAA1199 belongs to the TMEM2 family and contains 4 PbH1 repeats. It is expressed in the inner ear. It is expressed in cochlea and vestibule tissues and it may be involved in hearing. Defects in KIAA1199 may be a cause of non-syndromic hearing loss. It is also thought that KIAA1199 is a tumor suppressor that may be involved in establishing cellular mortality in normal human cells. Function: Potential NADPH-dependent oxidoreductase. May be involved in the regulation of neuronal survival, differentiation and axonal outgrowth. Subunit: Interacts with COBRA1, NOL12 and PRNP. Tissue Specificity: Down-regulated in the occipital lobe of an early stage Alzheimer disease patients. Similarity: Belongs to the P33MONOX family. SWISS: Q96A73 Gene ID: 57179 Database links: Entrez Gene: 57179 Human SwissProt: Q96A73 Human Unigene: 519783 Human |