產(chǎn)品編號(hào) | bs-17568R |
英文名稱 | Rabbit Anti-OTUD7A antibody |
中文名稱 | OTUD7A蛋白抗體 |
別 名 | C15orf16; OTU domain containing protein 7A; OTU domain-containing protein 7A; OTU7A_HUMAN; OTUD7; OTUD7A; Zinc finger protein Cezanne 2. |
研究領(lǐng)域 | 細(xì)胞生物 表觀遺傳學(xué) 泛素 |
抗體來(lái)源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | (predicted: Human,Mouse) |
產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理論分子量 | 101kDa |
細(xì)胞定位 | 細(xì)胞核 細(xì)胞漿 |
性 狀 | Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human OTUD7A: 501-600/926 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
產(chǎn)品介紹 |
Deubiquitinating enzymes (DUBs; see MIM 603478) are proteases that specifically cleave ubiquitin (MIM 191339) linkages, negating the action of ubiquitin ligases. OTUD7A belongs to a DUB subfamily characterized by an ovarian tumor (OTU) domain.[supplied by OMIM, May 2008] Function: Has deubiquitinating activity that is directed towards 'Lys-48' or 'Lys-63'-linked polyubiquitin chains. Hydrolyzes both linear and branched forms of polyubiquitin. Subcellular Location: Cytoplasm. Nucleus. Similarity: Belongs to the peptidase C64 family. Contains 1 A20-type zinc finger. Contains 1 OTU domain. SWISS: Q8TE49 Gene ID: 161725 Database links: Entrez Gene: 161725 Human Omim: 612024 Human SwissProt: Q8TE49 Human Unigene: 355236 Human |