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Rabbit Anti-MOG1  antibody (bs-17704R)  
~~~促銷代碼KT202411~~~
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產(chǎn)品編號 bs-17704R
英文名稱 Rabbit Anti-MOG1  antibody
中文名稱 Ran結(jié)合蛋白MOG1抗體
別    名 DKFZp686F02139; homolog of yeast MOG1; HSPC165; HSPC236; likely ortholog of mouse RAN guanine nucleotide release factor; MGC110973; MOG 1; MOG1; MOG1 homolog; MOG1_HUMAN; RAN guanine nucleotide release factor; Ran-binding protein MOG1; RANGNRF; RANGRF.  
研究領(lǐng)域 心血管  細(xì)胞生物  信號轉(zhuǎn)導(dǎo)  結(jié)合蛋白  G蛋白信號  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Mouse,Rat (predicted: Human)
產(chǎn)品應(yīng)用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 20kDa
細(xì)胞定位 細(xì)胞核 細(xì)胞漿 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human MOG1: 81-150/186 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項(xiàng) This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 This gene encodes a protein that has been shown to function as a guanine nucleotide release factor in mouse and to regulate the expression and function of the Nav1.5 cardiac sodium channel in human. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2010]

Function:
May regulate the intracellular trafficking of RAN. In cardiac cells seems to regulate the cell surface localization of SCN5A.

Subunit:
Monomer (By similarity). Interacts with RAN, RAN-GTP and RAN-GDP. Forms a complex with RAN-GTP and RANBP1 (By similarity). Interacts with the cytoplasmic loop 2 of SCN5A.

Subcellular Location:
Nucleus. Cytoplasm. Shuttles between the nucleus and cytoplasm.

Tissue Specificity:
Isoform 1 and isoform 2 are ubiquitously expressed.

Similarity:
Belongs to the MOG1 family.

SWISS:
Q9HD47

Gene ID:
29098

Database links:

Entrez Gene: 29098 Human

Entrez Gene: 57785 Mouse

Entrez Gene: 287419 Rat

Omim: 607954 Human

SwissProt: Q9HD47 Human

SwissProt: Q9JIB0 Mouse

Unigene: 408233 Human

Unigene: 371612 Mouse



產(chǎn)品圖片
Paraformaldehyde-fixed, paraffin embedded (Mouse brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (MOG1) Polyclonal Antibody, Unconjugated (bs-17704R) at 1:500 overnight at 4°C, followed by a conjugated secondary (sp-0023) for 20 minutes and DAB staining.
Paraformaldehyde-fixed, paraffin embedded (Mouse testis); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (MOG1) Polyclonal Antibody, Unconjugated (bs-17704R) at 1:500 overnight at 4°C, followed by a conjugated secondary (sp-0023) for 20 minutes and DAB staining.
Paraformaldehyde-fixed, paraffin embedded (Rat testis); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (MOG1) Polyclonal Antibody, Unconjugated (bs-17704R) at 1:500 overnight at 4°C, followed by a conjugated secondary (sp-0023) for 20 minutes and DAB staining.
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