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Rabbit Anti-mu Crystallin  antibody (bs-17900R)  
~~~促銷代碼KT202411~~~
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產(chǎn)品編號 bs-17900R
英文名稱 Rabbit Anti-mu Crystallin  antibody
中文名稱 CRYM蛋白抗體
別    名 CRYM; CRYM_HUMAN; Crystallin mu; DFNA 40; DFNA40; Ketimine reductase; Mu crystallin homolog; Mu-crystallin homolog; NADP regulated thyroid hormone binding protein; NADP-regulated thyroid-hormone-binding protein; OTTHUMP00000115878; THBP; Thiomorpholine carboxylate dehydrogenase.  
研究領域 細胞生物  發(fā)育生物學  生長因子和激素  結(jié)合蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human,Mouse,Rat,Pig,Sheep,Cow,Cat)
產(chǎn)品應用 IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 34kDa
細胞定位 細胞漿 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human mu Crystallin: 231-314/314 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 Crystallins are separated into two classes: taxon-specific and ubiquitous. The former class is also called phylogenetically-restricted crystallins. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. This gene encodes a taxon-specific crystallin protein that binds NADPH and has sequence similarity to bacterial ornithine cyclodeaminases. The encoded protein does not perform a structural role in lens tissue, and instead it binds thyroid hormone for possible regulatory or developmental roles. Mutations in this gene have been associated with autosomal dominant non-syndromic deafness. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2010]

Function:
Binds thyroid hormone. Presumably involved in the regulation of the free intracellular concentration of triiodothyronine and access to its nuclear receptors.

Subcellular Location:
Cytoplasm.

Tissue Specificity:
Expressed in neural tissue, muscle and kidney.

Similarity:
Belongs to the ornithine cyclodeaminase family.

SWISS:
Q14894

Gene ID:
1428

Database links:

Entrez Gene: 1428 Human

Entrez Gene: 505167 Cow

Entrez Gene: 12971 Mouse

Entrez Gene: 117024 Rat

Omim: 123740 Human

SwissProt: Q14894 Human

SwissProt: O54983 Mouse

SwissProt: Q9QYU4 Rat

Unigene: 924 Human

Unigene: 9114 Mouse

Unigene: 24561 Rat



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