| 產(chǎn)品編號(hào) | bs-18217R |
| 英文名稱 | Rabbit Anti-Neurotrypsin antibody |
| 中文名稱 | 神經(jīng)胰蛋白酶抗體 |
| 別 名 | BSSP 3; BSSP3; Leydin; MGC12722; MOTOPSIN; MRT1; NETR_HUMAN; Neurotrypsin; protease, serine, 12 (neurotrypsin, motopsin); Prss12; Serine protease 12. |
| 研究領(lǐng)域 | 細(xì)胞生物 神經(jīng)生物學(xué) 泛素 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human) |
| 產(chǎn)品應(yīng)用 | ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 95kDa |
| 細(xì)胞定位 | 分泌型蛋白 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human Neurotrypsin: 401-500/875 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
This gene encodes a member of the trypsin family of serine proteases. Studies in mouse suggest that the encoded enzyme may be involved in structural reorganizations associated with learning and memory. The enzyme is also expressed in Leydig cells in the testis, but its function in this tissue is unknown. Defects in this gene are a cause of mental retardation autosomal recessive type 1 (MRT1). [provided by RefSeq, Jul 2010] Function: Plays a role in neuronal plasticity and the proteolytic action may subserve structural reorganizations associated with learning and memory operations. Subcellular Location: Secreted. Tissue Specificity: Brain and Leydig cells of the testis. DISEASE: Defects in PRSS12 are the cause of mental retardation autosomal recessive type 1 (MRT1) [MIM:249500]. Mental retardation is a mental disorder characterized by significantly sub-average general intellectual functioning associated with impairments in adaptative behavior and manifested during the developmental period. Non-syndromic mental retardation patients do not manifest other clinical signs. Similarity: Belongs to the peptidase S1 family. Contains 1 kringle domain. Contains 1 peptidase S1 domain. Contains 4 SRCR domains. SWISS: P56730 Gene ID: 8492 Database links: Entrez Gene: 8492 Human Entrez Gene: 19142 Mouse SwissProt: P56730 Human SwissProt: O08762 Mouse Unigene: 445857 Human Unigene: 9431 Mouse Unigene: 86653 Rat |
