| 產(chǎn)品編號(hào) | bs-18225R |
| 英文名稱 | Rabbit Anti-LETM2 antibody |
| 中文名稱 | 線粒體LETM2抗體 |
| 別 名 | LETM1 and EF hand domain containing protein 2; LETM1 and EF-hand domain-containing protein 2; LETM1 domain containing protein LETM2 mitochondrial; LETM1 domain-containing protein LETM2; Letm2; LETM2_HUMAN; Leucine zipper EF hand containing transmembrane protein 1 like; Leucine zipper EF hand containing transmembrane protein 2; Leucine zipper-EF-hand-containing transmembrane protein 1-like; mitochondrial. |
| 研究領(lǐng)域 | 細(xì)胞生物 免疫學(xué) 線粒體 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human,Mouse,Rat,Rabbit,Pig,Cow,Dog,Horse) |
| 產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 53kDa |
| 細(xì)胞定位 | 細(xì)胞漿 線粒體 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human LETM2: 201-300/491 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
LETM2 is a 491 amino acid protein that is localized to the mitochondrial membrane and contains one LETM1 domain. Despite its name, LETM2, which is preferentially expressed in sperm and testis, does not contain any EF-hand domains. There are four isoforms of LETM2 that are produced as a result of alternative splicing events. A homolog of LETM2, LETM1 is thought to be involved in maintaining normal mitochondrial function and overall cell viability. Deletions in the gene encoding LETM1 are associated with Wolf-Hirschhorn syndrome (WHS), a congenital syndrome characterized by a number of abnormalities, including mental retardation, seizures, heart defects, fused teeth, hearing loss, a webbed neck and renal abnormalities. The LETM2 gene is located on chromosome 8, which is made up of nearly 146 million bases and encodes about 800 genes. Subcellular Location: Mitochondrion inner membrane. Similarity: Contains 1 LETM1 domain. SWISS: Q2VYF4 Gene ID: 137994 Database links: Entrez Gene: 137994 Human GenBank: NP_653253.1 Human SwissProt: Q2VYF4 Human Unigene: 696457 Human Unigene: 734005 Human |
