產(chǎn)品編號 | bs-18437R |
英文名稱 | Rabbit Anti-LSM14A/C19orf13 antibody |
中文名稱 | LSM14A蛋白抗體 |
別 名 | AlphaSNBP; C19orf13; Chromosome 19 open reading frame 13; DKFZp434D1335; FAM61A; Family with sequence similarity 61 member A; hRAP55; hRAP55A; LS14A_HUMAN; LSM14 homolog A (SCD6 S cerevisiae); LSM14 homolog A; LSM14A; Protein FAM61A; Protein LSM14 homolog A; Protein SCD6 homolog; Putative alpha synuclein binding protein; Putative alpha-synuclein-binding protein; RAP55; RNA associated protein 55; RNA-associated protein 55A; SCD6 homolog A (S cerevisiae). |
研究領(lǐng)域 | 細(xì)胞生物 轉(zhuǎn)運(yùn)蛋白 結(jié)合蛋白 表觀遺傳學(xué) |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | (predicted: Human,Mouse,Rat,Rabbit,Pig,Sheep,Cow,Chicken,Dog,Cat,GuineaPig,Danio) |
產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理論分子量 | 50kDa |
細(xì)胞定位 | 細(xì)胞漿 |
性 狀 | Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human LSM14A/C19orf13: 301-400/463 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
產(chǎn)品介紹 |
Sm-like proteins were identified in a variety of organisms based on sequence homology with the Sm protein family (see SNRPD2; 601061). Sm-like proteins contain the Sm sequence motif, which consists of 2 regions separated by a linker of variable length that folds as a loop. The Sm-like proteins are thought to form a stable heteromer present in tri-snRNP particles, which are important for pre-mRNA splicing.[supplied by OMIM, Mar 2008] Function: Essential for formation of P-bodies, cytoplasmic structures that provide storage sites for non-translating mRNAs. Subunit: Component of a ribonucleoprotein (RNP) complex. Subcellular Location: Cytoplasm. Cytoplasm > P-body. Targeted to stress granules (SGs) in response to cellular stress. Post-translational modifications: Phosphorylated upon DNA damage, probably by ATM or ATR. Similarity: Belongs to the LSM14 family. Contains 1 DFDF domain. SWISS: Q8ND56 Gene ID: 26065 Database links: Entrez Gene: 26065 Human Entrez Gene: 67070 Mouse Omim: 610677 Human SwissProt: Q8ND56 Human SwissProt: Q8K2F8 Mouse Unigene: 407368 Human Unigene: 276503 Mouse |