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Rabbit Anti-LYPD1  antibody (bs-18570R)  
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產(chǎn)品編號 bs-18570R
英文名稱 Rabbit Anti-LYPD1  antibody
中文名稱 LYPD1蛋白抗體
別    名 FLJ41033; LY6/PLAUR domain containing 1; Ly6/PLAUR domain-containing protein 1; Lypd1; LYPD1_HUMAN; LYPDC1; MGC29643; PHTS; Putative HeLa tumor suppressor.  
研究領(lǐng)域 細胞生物  細胞凋亡  表觀遺傳學  細胞膜蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human,Mouse,Rat,Rabbit)
產(chǎn)品應(yīng)用 IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 13kDa
細胞定位 細胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human LYPD1: 51-141/141 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 LYPD1 is a 141 amino acid protein that contains one UPAR/Ly6 domain. LYPD1 is a cell membrane protein expressed as three isoforms and encoded by a gene mapping to human chromosome 2. As the second largest human chromosome, chromosome 2 makes up approximately 8% of the human genome and contains 237 million bases encoding over 1,400 genes. A number of genetic diseases are linked to genes on chromosome 2. Harlequin icthyosis, a rare skin deformity, is associated with mutations in the ABCA12 gene. The lipid metabolic disorder sitosterolemia is associated with ABCG5 and ABCG8. An extremely rare recessive genetic disorder, Alstr鰉 syndrome, is related to mutations in the ALMS1 gene. Chromosome 2 contains a probable vestigial second centromere as well as vestigial telomeres, which gives credence to the hypothesis that human chromosome 2 formed as a result of an ancient fusion of two ancestral chromosomes, which are still present in modern day apes.

Subcellular Location:
Cell membrane.

Similarity:
Contains 1 UPAR/Ly6 domain.

SWISS:
Q8N2G4

Gene ID:
116372

Database links:

Entrez Gene: 116372 Human

Entrez Gene: 72585 Mouse

Entrez Gene: 360838 Rat

Omim: 610450 Human

SwissProt: Q8N2G4 Human

SwissProt: Q8BLC3 Mouse

SwissProt: Q66H42 Rat

Unigene: 432395 Human

Unigene: 741324 Human

Unigene: 490405 Mouse

Unigene: 231867 Rat



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