| 產(chǎn)品編號 | bs-18797R |
| 英文名稱 | Rabbit Anti-MEST antibody |
| 中文名稱 | 中胚層特異性轉(zhuǎn)錄同源蛋白MEST抗體 |
| 別 名 | DKFZp686L18234; EC 3.-.-.-; Mesoderm specific transcript (mouse) homolog; Mesoderm specific transcript homolog (mouse); Mesoderm-specific transcript homolog protein; MEST; MEST_HUMAN; MGC111102; MGC8703; OTTHUMP00000210362; OTTHUMP00000210364; OTTHUMP00000210367; Paternally expressed gene 1; Paternally-expressed gene 1 protein; PEG1. |
| 研究領(lǐng)域 | 細(xì)胞生物 免疫學(xué) 轉(zhuǎn)錄調(diào)節(jié)因子 淋巴細(xì)胞 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human,Mouse,Rat,Pig,Cow,Dog,Horse) |
| 產(chǎn)品應(yīng)用 | WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 39kDa |
| 細(xì)胞定位 | 細(xì)胞漿 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human MEST: 101-200/335 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
This gene encodes a member of the alpha/beta hydrolase superfamily. It is imprinted, exhibiting preferential expression from the paternal allele in fetal tissues, and isoform-specific imprinting in lymphocytes. The loss of imprinting of this gene has been linked to certain types of cancer and may be due to promotor switching. The encoded protein may play a role in development. Alternatively spliced transcript variants encoding multiple isoforms have been identified for this gene. Pseudogenes of this gene are located on the short arm of chromosomes 3 and 4, and the long arm of chromosomes 6 and 15. [provided by RefSeq, Dec 2011] Subcellular Location: Endoplasmic reticulum membrane. Tissue Specificity: Highly expressed in hydatidiform moles, but barely expressed in dermoid cysts. Biallelic expression is detected in blood lymphocytes. Seems to imprinted in an isoform-specific manner rather than in a tissue-specific manner in lymphocytes. Isoform 1 is expressed only from the paternal allele. Isoform 2 is expressed from both the paternal allele and the maternal allele. Similarity: Belongs to the AB hydrolase superfamily. SWISS: Q5EB52 Gene ID: 4232 Database links: Entrez Gene: 4232 Human Entrez Gene: 17294 Mouse Omim: 601029 Human SwissProt: Q5EB52 Human SwissProt: Q07646 Mouse Unigene: 270978 Human Unigene: 59431 Rat |
