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Rabbit Anti-Aquaporin 5  antibody (bs-10927R)  
~~~促銷代碼KT202411~~~
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產(chǎn)品編號 bs-10927R
英文名稱 Rabbit Anti-Aquaporin 5  antibody
中文名稱 水通道蛋白5抗體
別    名 Aquaporin 5; AQP5; AQP 5; AQP-5; AQP5_HUMAN; Aquaporin-5.  
Specific References  (2)     |     bs-10927R has been referenced in 2 publications.
[IF=3.266] Dai TQ et al. In vitro transdifferentiation of adipose tissue-derived stem cells into salivary gland acinar-like cells. Am J Transl Res. 2019 May 15;11(5):2908-2924.  ICF&WB ;  Mouse.  
[IF=2.027] Ba F et al. Lipoxin A4 ameliorates alveolar fluid clearance disturbance in lipopolysaccharide-induced lung injury via aquaporin 5 and MAPK signaling pathway. J Thorac Dis 2019;11(8):3599-3608  WB ;  Mouse.  
研究領(lǐng)域 信號轉(zhuǎn)導(dǎo)  通道蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human,Mouse,Rat (predicted: Pig)
產(chǎn)品應(yīng)用 WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 29kDa
細(xì)胞定位 細(xì)胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Aquaporin 5: 151-250/265 <Extracellular>
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項(xiàng) This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 Aquaporin 5 (AQP5) is a water channel protein. Aquaporins are a family of small integral membrane proteins related to the major intrinsic protein (MIP or AQP0). Aquaporin 5 plays a role in the generation of saliva, tears and pulmonary secretions. AQP0, AQP2, AQP5, and AQP6 are closely related and all map to 12q13. [provided by RefSeq, Jul 2008]

Function:
Forms a water-specific channel. Implicated in the generation of saliva, tears, and pulmonary secretions.

Subcellular Location:
Membrane; Multi-pass membrane protein.

Similarity:
Belongs to the MIP/aquaporin (TC 1.A.8) family.

SWISS:
P55064

Gene ID:
362

Database links:

Entrez Gene: 362 Human

Entrez Gene: 11830 Mouse

Entrez Gene: 25241 Rat

Omim: 600442 Human

SwissProt: P55064 Human

SwissProt: Q9WTY4 Mouse

SwissProt: P47864 Rat

Unigene: 298023 Human

Unigene: 45580 Mouse

Unigene: 10066 Rat




產(chǎn)品圖片
Sample: Eye (Rat) Lysate at 40 ug Primary: Anti-Aquaporin 5 (bs-10927R) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 29 kD Observed band size: 29 kD
Tissue/cell: human laryngocarcinoma; 4% Paraformaldehyde-fixed and paraffin-embedded; Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,C-0005) at 37℃ for 20 min; Incubation: Anti-Aquaporin Polyclonal Antibody, Unconjugated(bs-10927R) 1:500, overnight at 4°C, followed by conjugation to the secondary antibody(SP-0023) and DAB(C-0010) staining
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