| 產(chǎn)品編號 | bs-10970R |
| 英文名稱 | Rabbit Anti-ANGPTL6 antibody |
| 中文名稱 | 血管生成素相關(guān)蛋白6抗體 |
| 別 名 | ARP5; AGF; Angiopoietin like 6; Angiopoietin like Protein 6; Angiopoietin related Growth Factor; Angiopoietin related protein 5; Angiopoietin-like protein 6; Angiopoietin-related growth factor; Angiopoietin-related protein 5; Angiopoietin-related protein 6; ANGL6_HUMAN; Angptl6; ARP5. |
| 研究領(lǐng)域 | 心血管 細(xì)胞生物 血管內(nèi)皮細(xì)胞 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | Mouse (predicted: Human,Rat,Rabbit,Sheep,Horse) |
| 產(chǎn)品應(yīng)用 | WB=1:500-2000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 49kDa |
| 細(xì)胞定位 | 分泌型蛋白 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human ANGPTL6: 371-470/470 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
Angptl6 (angiopoietin-like 6) is a 470 amino acid secreted protein that contains one fibrinogen C-terminal domain and is a member of the angiopoietin-like family. Expressed abundantly in liver and present at lower levels in testis, kidney, heart, brain and lung, Angptl6 plays a role in wound healing and is also thought to promote neovascularization and enhance the chemotactic activity of endothelial cells. Additionally, Angptl6 may be involved in epidermal proliferation, remodeling and regeneration and may be able to counteract obesity by increasing energy expenditure. Human Angptl6 shares 74% amino acid identity with its mouse counterpart, suggesting a conserved role between species. The gene encoding Angptl6 maps to human chromosome 19, which is the genetic home for a number of immunoglobulin superfamily members, including the killer cell and leukocyte Ig-like receptors, a number of ICAMs, the CEACAM and PSG family and Fc receptors (FcRs). Function: May play a role in the wound healing process. May promote epidermal proliferation, remodeling and regeneration. May promote the chemotactic activity of endothelial cells and induce neovascularization. May counteract high-fat diet-induced obesity and related insulin resistance through increased energy expenditure. Subcellular Location: Secreted (Probable). Similarity: Contains 1 fibrinogen C-terminal domain. SWISS: Q8NI99 Gene ID: 83854 Database links: Entrez Gene: 83854 Human Entrez Gene: 70726 Mouse Omim: 609336 Human SwissProt: Q8NI99 Human SwissProt: Q8R0Z6 Mouse Unigene: 712850 Human Unigene: 34019 Mouse |
| 產(chǎn)品圖片 |
Sample:
Lane 1: Mouse Liver tissue lysates
Lane 2: Mouse Cerebrum tissue lysates
Primary: Anti-ANGPTL6 (bs-10970R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 49 kDa
Observed band size: 56 kDa
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